Pain in Children With ADHD: Mechanisms, Clinical Presentation, and Implications for Assessment and Management

Maria Rosaria Muzio1, Alessandro Vittori2, Teresa Grimaldi Capitello3

  • 1Division of Infantile Neuropsychiatry, UOMI-Maternal and Infant Health, ASL NA3 SUD Torre del Greco, Naples, Italy.

Insights

Children with attention-deficit/hyperactivity disorder (ADHD) may experience and express pain differently. Tailoring pain management to their neurodevelopmental profile is crucial for effective care.

Area of Science:

  • Pediatric neurology
  • Developmental psychology
  • Pain research

Background:

  • Pain assessment and management are challenging in children, especially those with neurodevelopmental disorders like attention-deficit/hyperactivity disorder (ADHD).
  • ADHD involves alterations in attention, executive function, and emotional regulation, domains critical to pain perception and expression.
  • Children with ADHD may exhibit atypical pain experiences, behaviors, and face significant hurdles in pain management.

Purpose of the Study:

  • To critically examine the neurobiological, psychological, and clinical interactions between ADHD and pain in children.
  • To synthesize fragmented literature on pediatric ADHD and pain across various study types.
  • To propose future directions for child-centered pain care.

Main Methods:

  • This study employed a narrative review approach.
  • It critically examined existing literature on the interplay between ADHD and pain in pediatric populations.
  • The review synthesized findings from experimental, clinical, and behavioral studies.

Main Results:

  • Proposed mechanisms linking ADHD to altered pain processing were discussed.
  • Evidence on pain perception and expression in children with ADHD was summarized.
  • Clinically relevant pain conditions and assessment/management challenges were explored.

Conclusions:

  • ADHD should be viewed as a modifier of pain experience and a potential contributor to chronification, not just a comorbidity.
  • Adapting pain assessment and management strategies to the specific neurodevelopmental profile of pediatric patients is essential.
  • Future research should focus on function- and child-centered pain care.
Abstract

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