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Updated: Apr 30, 2026

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
Published on: August 16, 2018
[Synthetic Drug: Pregabalin]
Hang Chen1, Xin Wang1, Hui Yan1
1Shanghai Key Laboratory of Forensic Medicine, Key Laboratory of Forensic Science, Ministry of Justice, Shanghai Forensic Service Platform, Academy of Forensic Science, Shanghai 200063, China.
None:
Pregabalin is a structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid. Currently, the number of deaths related to the misuse or abuse of pregabalin is gradually increa-sing, and there is an urgent need for relevant forensic toxicological information. Based on relevant do-mestic and international research, this article systematically reviews the pharmacological effects, toxicity data, poisoning symptoms, in vivo processes of pregabalin, as well as the toxicological data of various existing typical cases, with the aim of providing a reference for forensic identification.
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