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Updated: Apr 30, 2026

Preparation and Characterization of Lipophilic Doxorubicin Pro-drug Micelles
Published on: August 2, 2016
Polymer-doxorubicin Conjugates: Redefining Chemotherapy for Breast Cancer.
Sneha Kumari1, Aman Kumar2, Md Mustahidul Islam3
1Department of Pharmaceutical Quality Assurance, ISF College of Pharmacy, GT Road, Moga, 142001, Punjab, India.
Polymer drug conjugates (PDCs) enhance chemotherapy by creating macromolecular structures from small-molecule drugs. This targeted approach improves drug delivery to tumors and reduces side effects like cardiotoxicity.
Area of Science:
- Oncology
- Polymer Chemistry
- Pharmacology
Background:
- Conventional chemotherapeutics like doxorubicin (dox) face limitations including cardiotoxicity and multidrug resistance.
- Polymer drug conjugates (PDCs) are designed to overcome these limitations by modifying drug structures.
- The enhanced permeability and retention (EPR) effect is a key phenomenon exploited by PDCs for tumor targeting.
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09:09Synthesis of Aptamer-PEI-g-PEG Modified Gold Nanoparticles Loaded with Doxorubicin for Targeted Drug Delivery
Published on: June 23, 2020
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