Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

827
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
827
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

926
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
926
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

631
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
631
Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test01:22

Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test

271
In clinical practice, the direct measurement of hepatic blood flow to evaluate liver function presents significant challenges due to the intricate and specialized nature of the necessary techniques. Consequently, healthcare professionals often rely on empirical estimates derived from thorough patient examinations and liver function tests to gauge liver health. Among the tools at their disposal, the Child–Pugh and MELD scoring systems stand out for their ability to categorize and assess...
271

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Correction: Differentiating uterine adenosarcoma from endometrial polyps: MRI imaging features.

Abdominal radiology (New York)·2026
Same author

Impact of BRCA1/2 pathogenic variants on ipsilateral breast tumor recurrence and prognosis following breast-conserving surgery.

Breast cancer research and treatment·2026
Same author

Erratum: Genetic analysis of <i>Mycobacterium abscessus</i> reveals genomic diversity linked to global plasmid distribution.

iScience·2026
Same author

Beyond the brake: The subthalamic nucleus predominantly facilitates action in non-human primates.

Progress in neurobiology·2026
Same author

Pain and paresthesia patterns in degenerative cervical myelopathy: neuropathic sensory features and postoperative transitions in a prospective cohort.

The spine journal : official journal of the North American Spine Society·2026
Same author

Changes in re-excision rates after publication of guidelines defining positive margins for breast-conserving surgery: a collaborative study of the Japanese breast cancer society.

Breast cancer (Tokyo, Japan)·2026

Related Experiment Video

Updated: Apr 30, 2026

Reduced Complications after Arterial Reconnection in a Rat Model of Orthotopic Liver Transplantation
08:39

Reduced Complications after Arterial Reconnection in a Rat Model of Orthotopic Liver Transplantation

Published on: November 7, 2020

8.7K

Exploring Disease-Specific Waitlist Outcomes in Simultaneous Liver-Kidney Transplantation.

Rikako Oki1, Luckshi Rajendran2, Dean Yonghoon Kim2

  • 1Transplant Institute, Henry Ford Hospital, Detroit, MI, United States.

Transplant International : Official Journal of the European Society for Organ Transplantation
|April 29, 2026
PubMed
Summary

Liver etiology impacts waitlist outcomes in simultaneous liver-kidney transplants (SLKT). Patients with metabolic dysfunction-associated steatohepatitis (MASH) faced higher mortality than alcohol-related liver disease (ALD) before 2020, a disparity lessened by policy changes.

Keywords:
allocation policy changeliver etiologymetabolic dysfunction-associated steatohepatitissimultaneous liver-kidney transplantationwaitlist outcomes

More Related Videos

Heterotopic Auxiliary Whole Liver Rat Transplant Model Utilizing a Hepaticoureterostomy for Allograft Rejection Studies
11:25

Heterotopic Auxiliary Whole Liver Rat Transplant Model Utilizing a Hepaticoureterostomy for Allograft Rejection Studies

Published on: March 8, 2024

1.1K
Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model
12:49

Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model

Published on: August 17, 2022

2.9K

Related Experiment Videos

Last Updated: Apr 30, 2026

Reduced Complications after Arterial Reconnection in a Rat Model of Orthotopic Liver Transplantation
08:39

Reduced Complications after Arterial Reconnection in a Rat Model of Orthotopic Liver Transplantation

Published on: November 7, 2020

8.7K
Heterotopic Auxiliary Whole Liver Rat Transplant Model Utilizing a Hepaticoureterostomy for Allograft Rejection Studies
11:25

Heterotopic Auxiliary Whole Liver Rat Transplant Model Utilizing a Hepaticoureterostomy for Allograft Rejection Studies

Published on: March 8, 2024

1.1K
Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model
12:49

Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model

Published on: August 17, 2022

2.9K

Area of Science:

  • Transplantation research
  • Organ allocation policy
  • Hepatology

Background:

  • Current liver allocation systems do not consider liver etiology for simultaneous liver-kidney transplantation (SLKT).
  • Significant variations in waitlist outcomes exist among different liver disease etiologies.

Purpose of the Study:

  • To evaluate differences in waitlist outcomes for SLKT candidates based on major liver disease etiologies.
  • To assess the impact of the 2020 organ allocation policy change on these disparities.

Main Methods:

  • Analysis of 4,846 adult SLKT candidates listed in the Organ Procurement and Transplantation Network (OPTN) registry from January 2018 to March 2024.
  • Comparison of waitlist mortality and transplantation probability across liver disease groups (ALD, MASH, HCV, biliary).
  • Stratified analysis by MELD score and examination of pre- and post-2020 policy change outcomes.

Main Results:

  • Patients with MASH exhibited higher 1-year waitlist mortality compared to ALD (HR 1.300, p=0.012), particularly in the middle MELD score group (HR 1.365, p=0.044).
  • The disparity in waitlist mortality between MASH and ALD was more pronounced before the 2020 allocation policy change.
  • Waitlist outcomes varied significantly by liver etiology, with the 2020 policy potentially influencing these mortality disparities.

Conclusions:

  • Liver etiology is a critical factor influencing waitlist outcomes in SLKT.
  • The 2020 organ allocation policy revision may have mitigated pre-existing mortality disparities between MASH and ALD patients.
  • Future allocation strategies should consider liver-specific factors for equitable SLKT outcomes.