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Mapping Alzheimer's Disease Variants to Their Target Genes Using Computational Analysis of Chromatin Configuration
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Gene regulatory programs of cognitive resilience and pathogenesis in Alzheimer's disease

Collin Spencer1,2,3,4, 1,2,3,4, N M Prashant

  • 1Center for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Medrxiv : the Preprint Server for Health Sciences
|April 29, 2026
PubMed
Abstract

Keywords:
Alzheimer’s diseaseBCL6FLI1IKZF1IRF8NF-κBcognitive resiliencedorsolateral prefrontal cortexgene regulatory networksmicroglianetwork rewiringsingle-nucleus RNA-seqtranscription factors

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