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Non-ulcerated Necrotizing Sialometaplasia: A case series
Constanza Godoy-Latorre1, Macarena Rodríguez-Luengo2, Rolando Morales3
1Faculty of Dentistry, Universidad Andres Bello, Chile.
Journal of Clinical and Experimental Dentistry
|April 29, 2026
Summary
Necrotizing sialometaplasia, an inflammatory condition affecting salivary glands, can be challenging to diagnose early due to its non-ulcerated presentation. This report details three such cases, highlighting their clinical and histopathological features.
Area of Science:
- Oral Pathology
- Inflammatory Conditions
- Salivary Gland Diseases
Background:
- Necrotizing sialometaplasia is a rare inflammatory condition impacting salivary glands, primarily minor palatal glands.
- Early diagnosis is difficult as it may present without ulceration, mimicking other conditions.
- Despite being benign, it can resemble malignant processes clinically and histologically.
Purpose of the Study:
- To report three uncommon cases of non-ulcerated necrotizing sialometaplasia.
- To describe the clinical and histopathological characteristics of these challenging cases.
Main Methods:
- Case study review.
- Clinical examination and documentation.
- Histopathological analysis of affected tissues.
Main Results:
- Three cases of non-ulcerated necrotizing sialometaplasia were identified.
- Detailed clinical presentations and histopathological findings were documented for each case.
- The study emphasizes the diagnostic challenges posed by non-ulcerated presentations.
Conclusions:
- Non-ulcerated necrotizing sialometaplasia represents a diagnostic challenge.
- Awareness of these presentations is crucial for accurate diagnosis and to avoid misclassification as malignancy.
- Further case reports can aid in understanding the spectrum of this condition.
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