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Video Demonstration of ABCA12-Related Harlequin Ichthyosis in a Low-Resource Setting: Case Report and Review of Early
Chukwuka Elendu1, Dependable C Amaechi2, Tochi C Elendu3
1Federal University Teaching Hospital Owerri Nigeria.
Clinical Case Reports
|April 29, 2026
Abstract:
Harlequin ichthyosis is a rare, life-threatening neonatal dermatologic emergency that can be confidently diagnosed clinically at birth. Prompt recognition and early supportive management-including thermoregulation, fluid balance, infection prevention, and intensive skin care-are crucial determinants of survival, especially in low-resource settings where diagnostic and therapeutic options are limited.
Keywords:
ABCA12autosomal recessive congenital ichthyosisharlequin ichthyosislow‐resource settingsneonatal dermatologic emergency
