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Photo and Thermal Stable Lignin-Based Sunscreen Microcapsules.

Yuting Xiao1, Xiaojing Li1, Mingsong Zhou1

  • 1School of Chemistry and Chemical Engineering, State Key Laboratory of Advanced Papermaking and Paper-Based Materials, South China University of Technology, 381 Wushan Road, Tianhe District, Guangzhou 510640, China.

Chem & Bio Engineering
|April 29, 2026
PubMed
Summary
This summary is machine-generated.

Optimized lignin microcapsules offer enhanced natural sunscreen potential. These microcapsules improve photostability and biocompatibility, leading to effective sun protection factor (SPF) formulations.

Keywords:
UV-blockingcore materialsligninmicrocapsulesnatural sunscreen

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Area of Science:

  • Materials Science
  • Cosmetic Science
  • Biotechnology

Background:

  • Lignin microcapsules show promise as natural sunscreen agents.
  • Poor photostability and biocompatibility of core materials limit current applications.
  • Optimization of core formulation is crucial for improved stability and biocompatibility.

Purpose of the Study:

  • To optimize the core formulation of lignin microcapsules for enhanced stability and biocompatibility.
  • To develop a novel core formulation for lignin microcapsules incorporating four chemical sunscreen actives.
  • To evaluate the sun protection factor (SPF) and stability of the developed microcapsule-based sunscreen.

Main Methods:

  • Enzymatic hydrolysis lignin (EHL) microcapsules were synthesized using one-step ultrasonic cavitation.
  • A novel core formulation containing four chemical sunscreen actives was encapsulated.
  • Microcapsule size was optimized, and sunscreen creams were formulated with 10 wt % EHL microcapsules.

Main Results:

  • Optimal microcapsules with an average diameter of 383 nm were achieved.
  • Formulated creams demonstrated a sun protection factor (SPF) of 147.
  • The sunscreen exhibited excellent photo and thermal stability, with only a 14.7% decrease in SPF after 10 hours of UV irradiation and minimal change at 50 °C.

Conclusions:

  • Optimized EHL-based microcapsules offer improved photostability and thermal stability.
  • The developed microcapsules possess good biocompatibility, enhancing their potential for natural sunscreen applications.
  • This research paves the way for advanced natural sunscreen formulations with superior performance and safety.