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Updated: Apr 30, 2026

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Published on: April 21, 2022
Isolated primary pericardial sarcomatoid mesothelioma: a case report
Pouya Nezafati1, Ricardo Vilain2, Taranpreet Singh1
1Department of Cardiothoracic Surgery, John Hunter Hospital, Newcastle, NSW, Australia.
Primary pericardial mesothelioma is rare and often diagnosed late. This case shows progression from early-stage mesothelioma in situ to invasive sarcomatoid disease, emphasizing early diagnosis for better outcomes.
Area of Science:
- Oncology
- Thoracic Surgery
- Pathology
Background:
- Primary pericardial mesothelioma is a rare malignancy with nonspecific clinical and radiologic findings, leading to late diagnosis.
- Patients with a history of mediastinal radiotherapy are at increased risk.
- Recurrent pericardial effusions and constrictive pericarditis can be presenting symptoms.
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