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Ménière's Disease: A Tri-Decade Scoping Review of Treatment Trends and Evidence Quality
Ofir Zavdy1, Teeraya Piyajarawong1, Seamus Boyle1
1Department of Otolaryngology, University Health Network, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada.
Introduction:
Ménière's disease (MD) is a complex inner ear disorder defined by endolymphatic hydrops and a triad of episodic vertigo, fluctuating hearing loss, and tinnitus. Despite AAO-HNS diagnostic guidelines, disease heterogeneity and lack of treatment consensus persist.
Objective:
This study conducts a tri-decade scoping review (1994-2024) to evaluate the MD evidence base, shifts in management, and methodological rigor regarding AAO-HNS and CONSORT compliance.
Materials And Methods:
A systematic search of PubMed, CINAHL, and Cochrane (2014-2024) identified English-language RCTs and prospective cohorts involving adults. Studies were graded via the Oxford CEBM system, with guideline compliance analyzed using IBM SPSS v29.0. A scoping review framework was adopted to map the "Quality Paradox" between evidence hierarchy and reporting standards.
Results:
From 1344 publications, 257 studies met inclusion criteria. While research volume surged-with Level 2 studies quadrupling (p < 0.01) and Level 3 studies tripling (p < 0.05)-reporting standards significantly declined. Adherence to AAO-HNS diagnostic and treatment-outcome criteria dropped to 73% and 34%, respectively. Clinically, management shifted toward preservation-focused interventions, including hydrops-visualizing MRI, intratympanic steroids over gentamicin, and increased cochlear implantation, alongside a decline in positive-pressure device use.
Conclusion:
The MD evidence base increasingly favors non-ablative, patient-centered interventions. However, the validity of these advancements is threatened by a significant decline in reporting compliance. To safeguard the evidence base, journals must enforce standardized reporting as a nonnegotiable prerequisite for publication.
Level Of Evidence:
N/A.
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