Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Three-Dimensional Microscopy in Microbiology01:28

Three-Dimensional Microscopy in Microbiology

907
Three-dimensional imaging techniques are essential in cell biology, allowing researchers to visualize intricate cellular structures with high resolution. Two prominent methods, Differential Interference Contrast Microscopy (DIC) and Confocal Scanning Laser Microscopy (CSLM), provide distinct advantages for imaging live and thick specimens, respectively.Differential Interference Contrast MicroscopyDIC microscopy enhances contrast in transparent, unstained samples by converting phase...
907
Two-Dimensional Microscopy in Microbiology01:29

Two-Dimensional Microscopy in Microbiology

1.8K
Two-dimensional (2D) microscopy encompasses a range of optical techniques that capture images within a single focal plane, offering detailed representations of microscopic structures. These techniques are essential in biological and medical research, enabling the visualization of cellular and subcellular structures with different levels of contrast and specificity.There are several major types of 2D microscopy, each with strengths and applications.Bright-Field MicroscopyBright-field microscopy...
1.8K
Phase Contrast and Differential Interference Contrast Microscopy01:26

Phase Contrast and Differential Interference Contrast Microscopy

9.4K
Phase-Contrast Microscopes
In-phase-contrast microscopes, interference between light directly passing through a cell and light refracted by cellular components is used to create high-contrast, high-resolution images without staining. It is the oldest and simplest type of microscope that creates an image by altering the wavelengths of light rays passing through the specimen. Altered wavelength paths are created using an annular stop in the condenser. The annular stop produces a hollow cone of...
9.4K
Imaging Biological Samples with Optical Microscopy01:18

Imaging Biological Samples with Optical Microscopy

9.1K
Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
9.1K
Overview of Microscopy Techniques01:22

Overview of Microscopy Techniques

10.7K
The early pioneers of microscopy opened a window into the invisible world of microorganisms. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes that leveraged nonvisible light, such as fluorescence microscopy that uses an ultraviolet light source and electron microscopy that uses short-wavelength electron beams. These advances significantly improved magnification, image resolution, and contrast. By comparison, the...
10.7K
Super-resolution Fluorescence Microscopy01:37

Super-resolution Fluorescence Microscopy

12.3K
Super-resolution fluorescence microscopy (SRFM) provides a better resolution than conventional fluorescence microscopy by reducing the point spread function (PSF). PSF is the light intensity distribution from a point that causes it to appear blurred. Due to PSF, each fluorescing point appears bigger than its actual size, and it is the PSF interference of nearby fluorophores that causes the blurred image. Various approaches to achieving higher resolution through SRFM have recently been...
12.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Electricity generation from food wastes and microbial community structure in microbial fuel cells.

Bioresource technology·2013
Same author

Plasmon-enhanced photothermoelectric conversion in chemical vapor deposited graphene p-n junctions.

Journal of the American Chemical Society·2013
Same author

Rapid and sensitive detection of vinorelbine in the urine of tumor patients by capillary electrophoresis with tris(2,2'-bipyridyl)ruthenium(II)-based electrochemiluminescence assay.

Analytical sciences : the international journal of the Japan Society for Analytical Chemistry·2013
Same author

Synthesis and biological evaluation of 4-phenoxy-6,7-disubstituted quinolines possessing semicarbazone scaffolds as selective c-Met inhibitors.

Archiv der Pharmazie·2013
Same author

The effects of external electric field: creating non-zero first hyperpolarizability for centrosymmetric benzene and strongly enhancing first hyperpolarizability for non-centrosymmetric edge-modified graphene ribbon H2N-(3,3)ZGNR-NO2.

Journal of molecular modeling·2013
Same author

Msx2 plays a critical role in lens epithelium cell cycle control.

International journal of ophthalmology·2013

Related Experiment Video

Updated: Apr 30, 2026

Mixed Reality Technology and Three-Dimensional Printing in Teaching: Heart Anatomy as an Example
06:18

Mixed Reality Technology and Three-Dimensional Printing in Teaching: Heart Anatomy as an Example

Published on: April 18, 2025

1.1K

Enhancing Histological Learning Through Augmented Reality: A Comparative Study of Traditional Microscopy and AR-Based

Ran Xiao1, Xiaolei Chen1, Xiuli Yang1

  • 1Forensic Judicial Authentication Institute, Shenyang Medical College, Shenyang, China.

Clinical Anatomy (New York, N.Y.)
|April 29, 2026
PubMed
Summary
This summary is machine-generated.

Augmented reality (AR) enhances histology learning by improving knowledge retention and spatial skills compared to traditional microscopy. AR instruction also boosts motivation and practical performance in medical students.

Keywords:
augmented realitycognitive load theoryhistology educationmedical educationsmart educationspatial visualization

More Related Videos

Technical Approach for Infrared Tracking for Soft Tissue Navigation with a Holographic Head-Mounted Display and Preclinical Validation
10:25

Technical Approach for Infrared Tracking for Soft Tissue Navigation with a Holographic Head-Mounted Display and Preclinical Validation

Published on: September 2, 2025

645
High-Speed Ultraviolet Photoacoustic Microscopy for Histological Imaging with Virtual-Staining assisted by Deep Learning
09:31

High-Speed Ultraviolet Photoacoustic Microscopy for Histological Imaging with Virtual-Staining assisted by Deep Learning

Published on: April 28, 2022

4.2K

Related Experiment Videos

Last Updated: Apr 30, 2026

Mixed Reality Technology and Three-Dimensional Printing in Teaching: Heart Anatomy as an Example
06:18

Mixed Reality Technology and Three-Dimensional Printing in Teaching: Heart Anatomy as an Example

Published on: April 18, 2025

1.1K
Technical Approach for Infrared Tracking for Soft Tissue Navigation with a Holographic Head-Mounted Display and Preclinical Validation
10:25

Technical Approach for Infrared Tracking for Soft Tissue Navigation with a Holographic Head-Mounted Display and Preclinical Validation

Published on: September 2, 2025

645
High-Speed Ultraviolet Photoacoustic Microscopy for Histological Imaging with Virtual-Staining assisted by Deep Learning
09:31

High-Speed Ultraviolet Photoacoustic Microscopy for Histological Imaging with Virtual-Staining assisted by Deep Learning

Published on: April 28, 2022

4.2K

Area of Science:

  • Medical Education
  • Histology
  • Educational Technology

Background:

  • Histology learning involves complex 3D visualization from 2D images, posing a significant cognitive challenge for students.
  • Traditional microscopy methods may not fully address the spatial understanding difficulties inherent in histology.
  • Augmented reality (AR) presents a potential technological solution to enhance spatial learning in complex subjects.

Purpose of the Study:

  • To compare the effectiveness of augmented reality (AR)-assisted histology instruction versus traditional microscopy.
  • To evaluate the impact of AR on cognitive, motivational, and practical learning outcomes in medical students.
  • To assess long-term knowledge retention and spatial understanding in histology.

Main Methods:

  • A comparative educational study involving 152 second-year medical students.
  • Students were divided into two groups: traditional microscopy and AR-based instruction.
  • Outcomes including knowledge retention, spatial understanding, practical skills, cognitive load, and motivation were assessed at multiple time points.

Main Results:

  • The AR group showed significantly higher delayed knowledge retention and improved spatial understanding compared to the traditional group (p < 0.001).
  • AR-trained students demonstrated superior practical tissue identification accuracy and faster completion times.
  • AR instruction correlated with reduced extraneous cognitive load, increased germane load, and enhanced intrinsic motivation.

Conclusions:

  • Augmented reality (AR) is an effective complementary strategy for histology education.
  • AR integration can reduce cognitive load and improve spatial visualization skills in medical learners.
  • AR-assisted instruction promotes a more effective and learner-centered approach to histology education.