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Evaluation of DNA methylation-based age prediction accuracy in leukemia patients using a six-CpG model trained on

Kadriye Can1, Gonul Filoglu1, Gokhan Ersoy2

  • 1Department of Science, Institute of Forensic Sciences and Legal Medicine, Istanbul University-Cerrahpasa, Istanbul, 34500, Turkey.

Forensic Science, Medicine, and Pathology
|April 29, 2026
PubMed
Abstract

No abstract available in PubMed .

Keywords:
DNA methylationEpigenetic age predictionEpigenetic alterationsLeukemiaSNaPshot

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Epigenetic Regulation01:46

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Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
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Epigenetic Regulation

Epigenetic changes alter the physical structure of the DNA without changing the genetic sequence and often regulate whether genes are turned on or off. This regulation ensures that each cell produces only proteins necessary for its function. For example, proteins that promote bone growth are not produced in muscle cells. Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
X-chromosome...