Evaluating nurse-led self-regulation in multiple sclerosis management with an interactive web-based program: a...

This study aimed to evaluate the effect of the 'I Can Manage' an interactive web-based program that supports self-regulation under the leadership of nurses, application on self-management, fatigue and anxiety levels in individuals with Multiple Sclerosis (MS). This study is a parallel-group randomized controlled trial. Individuals with MS were randomly assigned to an intervention group (N = 38) and a control group (N = 38). The intervention group used 'I Can Manage' for eight weeks, while the control group did not receive any intervention. Data were collected using the Participant Identification Form, Multiple Sclerosis Self-Management Scale, Fatigue Severity Scale, State-Trait Anxiety Inventory, Program Usage Form, and Web Program Evaluation Form. The study was registered at ClinicalTrials database (NCT05393765). The time x group interaction for the self-management scores was significant and had a moderate effect size in favour of the intervention group (P < .01, pη2 = 0.114), whereas no significant changes were observed in the fatigue, state, and trait anxiety scores. A total of 86.8% of the participants used at least one feature of the program, and 93.9% found it easy to use and understand. 'I Can Manage' improved self-management in individuals with MS but did not lead to significant changes in fatigue or anxiety levels.