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Cancer Prevention02:59

Cancer Prevention

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Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
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Cancer Prevention02:59

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Combination Therapies and Personalized Medicine02:50

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Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
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Preventive Healthcare Services01:30

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Preventive healthcare services keep people healthy via frequent check-ups, screening, and counseling. They primarily aid in disease prevention rather than treating an acute or chronic illness. Preventive treatment also keeps individuals productive and energetic, allowing them to work well into their retirement years. Examples of preventive care services include:
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Cancer-Critical Genes II: Tumor Suppressor Genes01:05

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Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
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Updated: May 1, 2026

Standardized SDS-PAGE Workflow for Personalized Protein Corona Profiling in Early Cancer Detection
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Standardized SDS-PAGE Workflow for Personalized Protein Corona Profiling in Early Cancer Detection

Published on: December 19, 2025

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Impact of a Multidisciplinary Cancer Predisposition Program on Adherence With Screening Guidelines for Patients With

Rebecca Volmy1, Nina Linneman2, Sarah Linn3

  • 1Department of Pediatrics, Medical College of Wisconsin Affiliated Hospitals.

Journal of Pediatric Hematology/Oncology
|April 29, 2026
PubMed
Summary

A multidisciplinary Cancer Predisposition Program significantly improved adherence to cancer screening for new pediatric patients with cancer predisposition syndromes (CPSs). Established patients did not show similar improvements.

Keywords:
cancer predisposition syndromesgenetic cancer riskpediatric cancer predisposition syndromessurveillance

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Area of Science:

  • Pediatric Oncology
  • Genetics
  • Medical Informatics

Background:

  • Genetic testing is increasingly identifying pediatric cancer predisposition syndromes (CPSs).
  • Specialized care is needed for this growing patient population.
  • Multidisciplinary programs can potentially improve management of CPSs.

Purpose of the Study:

  • To evaluate the impact of a multidisciplinary Cancer Predisposition Program on adherence to recommended surveillance.
  • To assess if the program improved adherence for both new and established patients.

Main Methods:

  • Retrospective review of patient data.
  • Comparison of adherence rates before and after program implementation.
  • Analysis of screening adherence for new referrals versus established patients.

Main Results:

  • New patients referred to the program were 2.55 times more likely to adhere to surveillance recommendations.
  • Adherence rates for patients already within the medical system did not significantly improve post-program development.
  • The program demonstrated a positive impact on adherence for newly identified cases.

Conclusions:

  • A multidisciplinary Cancer Predisposition Program enhances adherence to recommended surveillance for new pediatric patients with CPSs.
  • Programmatic improvements are crucial for optimizing care in pediatric cancer genetics.
  • Further strategies may be needed to enhance adherence for established patient cohorts.