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Related Experiment Video

Updated: May 1, 2026

Utilizing Repetitive Transcranial Magnetic Stimulation to Improve Language Function in Stroke Patients with Chronic Non-fluent Aphasia
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[Therapy prospects for post-stroke aphasia].

A N Bogolepova1,2

  • 1Pirogov Russian National Research Medical University, Moscow, Russia.

Zhurnal Nevrologii I Psikhiatrii Imeni S.S. Korsakova
|April 29, 2026
PubMed
Summary
This summary is machine-generated.

Stroke survivors with aphasia can improve speech function faster with Cerebrolysin combined with speech therapy. This combination therapy aids neuroplasticity and enhances stroke rehabilitation outcomes.

Keywords:
Cerebrolysinneuroplasticitypost-stroke aphasiarehabilitationstroke

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Area of Science:

  • Neurology
  • Neuroscience
  • Pharmacology

Background:

  • Stroke is a primary cause of long-term disability globally.
  • Post-stroke aphasia affects roughly 30% of patients, significantly impacting quality of life and rehabilitation.
  • Neuroplasticity is key to stroke recovery, making neuroplasticity-stimulating agents a promising treatment avenue.

Purpose of the Study:

  • To evaluate the efficacy of Cerebrolysin as an adjunct to speech therapy for post-stroke aphasia.
  • To investigate the impact of Cerebrolysin on accelerating speech function recovery.
  • To assess the role of Cerebrolysin in enhancing overall stroke rehabilitation.

Main Methods:

  • The study involved patients with aphasia following acute ischemic stroke.
  • Participants received standard speech therapy combined with Cerebrolysin.
  • The Efficacy and Safety of Cerebrolysin in the Treatment of Aphasia After Acute Ischemic Stroke (ESCAS) study design was employed.

Main Results:

  • Combined speech therapy and Cerebrolysin significantly accelerated the recovery of speech functions.
  • Cerebrolysin demonstrated value as an adjunct therapy in stroke rehabilitation.
  • The treatment showed potential in improving outcomes for patients with post-stroke aphasia.

Conclusions:

  • Cerebrolysin, a drug activating neuroplasticity, combined with speech therapy, offers a promising approach for post-stroke aphasia.
  • This therapeutic strategy can expedite recovery and improve functional outcomes for stroke survivors.
  • Further research supports Cerebrolysin's role in enhancing stroke rehabilitation and mitigating cognitive deficits.