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Exploring the safe dwell time of peripheral venous catheters in pediatric patients: A prospective cohort study

Tao Wei1, Yan Tan2, Mei-Hong Hu2

  • 1Anesthesiology Department, Affiliated Cancer Hospital of Xiangya School of Medicine, Central south university/Hunan cancer hospital, Changsha, Hunan Province, China.

Journal of Pediatric Nursing
|April 29, 2026
PubMed

Insights

Peripheral venous catheter (PVC) dwell time in children has an inflection point around 136 hours for complications. Clinically indicated removal with monitoring is recommended over routine replacement for pediatric patients.

Area of Science:

  • Pediatric Medicine
  • Infectious Disease Control
  • Medical Device Safety

Background:

  • Peripheral venous catheters (PVCs) are crucial for pediatric care.
  • Catheter-related complications pose risks to young patients.
  • Current guidelines often recommend routine time-based replacement of PVCs.

Purpose of the Study:

  • To determine the safe dwell time for PVCs in pediatric patients.
  • To identify factors linked to catheter-related complications.
  • To evaluate the association between dwell time and complication risk.

Main Methods:

  • Prospective multicenter study involving 1527 pediatric patients (3-13 years).
  • PVCs were removed based on clinical indication, not routine time.
  • Nonlinear associations between dwell time and complications analyzed using logistic regression and restricted cubic splines.

Main Results:

  • 93.1% of PVCs were removed due to clinical need.
  • 44.0% of patients experienced complications, with median onset at 71 hours.
  • A nonlinear association between dwell time and complications was found, with an inflection point around 136 hours.

Conclusions:

  • Dwell time alone is not the sole risk factor for PVC complications in children.
  • Enhanced monitoring is advised beyond the 136-hour inflection point.
  • Clinically indicated removal with vigilant surveillance is supported over routine replacement.
Abstract

Keywords:
Catheterization, peripheralChild, hospitalizedComplicationsProspective studiesRisk factors

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