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Trends in asthma-related paediatric mortality
Isabel J Hardee1, Michael C Monuteaux2, Robert M Hoffmann2
1Emergency Medicine, Boston Children's Hospital Department of Pediatrics, Boston, Massachusetts, USA isabel.hardee@childrens.harvard.edu.
Thorax
|April 29, 2026
Summary
Paediatric asthma mortality rates remained stable from 1999-2023. However, asthma deaths were higher in males, older children, and Black children, indicating a need for targeted interventions.
Area of Science:
- Pediatric Mortality Trends
- Asthma Epidemiology
- Public Health Surveillance
Background:
- Asthma is a significant cause of death in children.
- Understanding temporal trends in pediatric asthma mortality is crucial for public health.
- Existing data on long-term trends in pediatric asthma deaths require further analysis.
Purpose of the Study:
- To analyze trends in pediatric asthma-related mortality in the US.
- To examine demographic disparities in pediatric asthma mortality.
- To identify specific age, sex, and racial groups with higher asthma mortality.
Main Methods:
- Cross-sectional analysis of US Centers for Disease Control (CDC) WONDER data.
- Data spanned from 1999 to 2023.
- Negative binomial regression used to assess temporal trends and group differences.
Main Results:
- A total of 5357 pediatric asthma deaths were recorded.
- The overall pediatric asthma mortality rate was stable at 3 per 1,000,000 children.
- Mortality rates were higher among males, children aged 10-19 years, and Black children compared to white children.
Conclusions:
- Pediatric asthma mortality rates have remained stable over the study period.
- Targeted interventions are needed to address disparities in asthma mortality among Black children.
- Future advancements in pediatric asthma treatment should focus on reducing mortality and improving outcomes for vulnerable populations.
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