Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The JR blood group system: from discovery to the clinic.

PeerJ·2026
Same author

Seaming the Bioelectronic Interface: Mechanisms, Strategies, and Validation Standards for Durable Poly(3,4-ethylenedioxythiophene)-Based Coating Adhesion.

ACS nano·2026
Same author

Modulation of place cells using targeted stimulation with bidirectional microelectrode arrays enhances spatial learning speed in mice.

Fundamental research·2026
Same author

From Light to Logic: Micron-Scale Doping Enables Flexible Organic Circuits.

Polymer science & technology (Washington, D.C.)·2026
Same author

A temporal-spectral dual-stream anti-noise bearing fault diagnosis model based on adaptive mode decomposition.

Scientific reports·2026
Same author

Interactions of Oat β-Glucan, Protein, and Starch Under High Hydrostatic Pressure and Their Influence on Starch Properties.

Gels (Basel, Switzerland)·2026
Same journal

Forced changes in a Tibetan lake ecosystem over the past millennium.

Nature communications·2026
Same journal

Time-Temperature Superposition Principle Serving as a Design Tool for Tailored MOF-Crystal Glass Composite Membranes.

Nature communications·2026
Same journal

Simultaneous nanoscale imaging of local conductivity and chemical potential in a quantum Hall isospin ferromagnet.

Nature communications·2026
Same journal

A family of archaeal hibernation factors that bind in tandem and protect ribosomes in dormant cells.

Nature communications·2026
Same journal

Surface energy-driven perpendicular gradient structure in flexible composite dielectrics for high-temperature capacitive energy storage.

Nature communications·2026
Same journal

Severe droughts in Senegal are linked to increased family reunification at migration destinations in Europe.

Nature communications·2026
See all related articles
  1. Home
  3. Dynamic Neuronal Ensembles Encode Burst-suppression Revealed By Cortex-wide Optical-electrical Interfaces.
  1. Home
  3. Dynamic Neuronal Ensembles Encode Burst-suppression Revealed By Cortex-wide Optical-electrical Interfaces.

Related Experiment Video

Author Spotlight: Advancing Large-Scale Neural Dynamics Through HD-MEA Technology
09:44

Author Spotlight: Advancing Large-Scale Neural Dynamics Through HD-MEA Technology

Published on: March 8, 2024

4.6K

Dynamic neuronal ensembles encode burst-suppression revealed by cortex-wide optical-electrical interfaces.

Guihua Xiao1,2,3, Mo Yang4, Lingbo Li5,6

  • 1Beijing National Research Center for Information Science and Technology, Tsinghua University, Beijing, China. xiaoguihua@tsinghua.edu.cn.

Nature Communications
|April 29, 2026

View abstract on PubMed

Summary
This summary is machine-generated.

Researchers explored burst suppression, a state of unconsciousness, using a novel dual-modal system. They discovered distinct neuronal ensembles that coordinate activity during these events, revealing the brain

More Related Videos

Optical Recording of Suprathreshold Neural Activity with Single-cell and Single-spike Resolution
08:48

Optical Recording of Suprathreshold Neural Activity with Single-cell and Single-spike Resolution

Published on: September 5, 2012

11.3K
Multiscale Investigations of Cortical Processing by Integrating Laminar Polytrodes and Optogenetics with Micro Electrocorticography in Rodents
07:52

Multiscale Investigations of Cortical Processing by Integrating Laminar Polytrodes and Optogenetics with Micro Electrocorticography in Rodents

Published on: May 23, 2025

997

Related Experiment Videos

Author Spotlight: Advancing Large-Scale Neural Dynamics Through HD-MEA Technology
09:44

Author Spotlight: Advancing Large-Scale Neural Dynamics Through HD-MEA Technology

Published on: March 8, 2024

4.6K
Optical Recording of Suprathreshold Neural Activity with Single-cell and Single-spike Resolution
08:48

Optical Recording of Suprathreshold Neural Activity with Single-cell and Single-spike Resolution

Published on: September 5, 2012

11.3K
Multiscale Investigations of Cortical Processing by Integrating Laminar Polytrodes and Optogenetics with Micro Electrocorticography in Rodents
07:52

Multiscale Investigations of Cortical Processing by Integrating Laminar Polytrodes and Optogenetics with Micro Electrocorticography in Rodents

Published on: May 23, 2025

997

Area of Science:

  • Neuroscience
  • Systems Neuroscience
  • Computational Neuroscience

Background:

  • Burst suppression is a common pattern of brain activity during unconsciousness.
  • The precise neuronal organization underlying burst suppression is not fully understood.

Purpose of the Study:

  • To investigate the cortex-wide neuronal dynamics during burst suppression.
  • To understand the organization of neuronal ensembles during anesthesia-induced unconsciousness.

Main Methods:

  • Development and application of an integrated Cortex-wide Optical-electrical Dual-modal Explorer (CODE) system.
  • Simultaneous electrocorticography (ECoG) and calcium imaging in mice under isoflurane anesthesia.
  • Analysis of neuronal synchrony, functional connectivity, and signal propagation.

Main Results:

  • Identified distinct neuronal ensembles that associate with burst or suppression events.
  • Burst events showed high synchrony and connectivity; suppression events showed asynchronous activity and reduced connectivity.
  • Observed sequential, directional propagation of activity across cortical regions during state transitions.

Conclusions:

  • Revealed the single-neuron-to-population architecture of burst suppression.
  • Demonstrated how integrated optical-electrical measurements facilitate large-scale interrogation of cortical dynamics.
  • Provided insights into the dynamic recruitment and reactivation of neuronal ensembles during unconsciousness.