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Updated: May 5, 2026

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
Published on: September 20, 2018
Differences in bleeding outcome capture between electronic health record review using natural language processing and
Signe H Biørn1,2, Anne L Lyster1,2, Rasmus S Hansen1,3
1Department of Clinical Biochemistry, Odense University Hospital, Odense, Denmark.
Impact:
NLP applied to paediatric EHRs identified substantially more clinically documented bleeding events than ICD-10 coding. Demonstrates considerable loss of clinically assessed bleeding information when relying on administrative datasets alone. Shows that narrative-based ascertainment captures the full spectrum of documented bleeding events not transferred to structured coding. Provides a scalable method for documentation-based bleeding surveillance in hospitalised children. Supports use of NLP to improve outcome ascertainment in research, safety monitoring, and quality registries.

