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Prevalence, characteristics, and surgical outcomes of cardiac masses: a 6-year retrospective cohort study
Mohsen Mir Mohammadsadeghi1, Babak Darakhshandeh1, Marjan Jamalian2
1Chamran Cardiovascular Medical and Research Hospital, Department of Cardiac Surgery, Isfahan University of Medical Sciences, Isfahan, Iran.
Insights
Surgical removal of cardiac masses (CMs) showed no significant short-term functional impairment. Postoperative echocardiography is valuable for assessing cardiac structure and function after CM resection.
Area of Science:
- Cardiology
- Cardiac Surgery
- Diagnostic Imaging
Background:
- Cardiac masses (CMs) present diagnostic challenges.
- Echocardiography is the primary diagnostic tool for CMs.
- Limited data exist on postoperative echocardiographic changes and regional Iranian data.
Purpose of the Study:
- To evaluate echocardiographic changes after CM surgical resection.
- To characterize clinical and histopathological features of CMs in an Iranian cohort.
Main Methods:
- Retrospective cohort study of 75 patients (2018-2023).
- Transthoracic echocardiography and histopathology for diagnosis.
- Comparison of pre- and postoperative echocardiographic parameters.
Main Results:
- Most CMs were benign (69.3%), primarily myxomas (52%).
- Left atrium was the most common location (58.2%).
- Significant postoperative change noted in right ventricular size (p=0.008); other parameters unchanged.
Conclusions:
- Surgical resection of CMs did not lead to significant short-term functional impairment.
- Postoperative echocardiography is valuable for assessment.
- Novel regional data from Iran provided; calls for larger prospective studies.
Background:
Cardiac masses (CMs) pose a significant diagnostic challenge. Echocardiography is the primary modality for both initial evaluation and perioperative assessment due to its accessibility and ability to assess cardiac structure and function. However, data on postoperative echocardiographic changes remain limited. Also, comprehensive regional data, particularly from Iran, are scarce, and studies evaluating paired pre- and postoperative echocardiographic parameters are lacking. Accordingly, this study aimed to evaluate echocardiographic changes following surgical resection and to characterize the clinical and histopathological features of CMs in a regional cohort.
Methods:
This retrospective cohort study (2018-2023) included 75 patients with surgically resected CMs from two tertiary centers. Diagnoses were confirmed by transthoracic echocardiography and histopathology. Pre- and postoperative echocardiographic parameters were compared, and clinical and demographic data were obtained from medical records. Paired statistical tests were used, with p < 0.05 considered significant.
Results:
Among 75 patients (mean age 53.6 ± 17.4 years; 50.7% male), most had benign tumors (69.3%), predominantly myxomas (52%). The left atrium was the most common location (58.2%). A significant postoperative change was observed in right ventricular size distribution (p = 0.008), while other echocardiographic parameters remained unchanged.
Conclusion:
Surgical resection of CMs was not associated with significant short-term functional impairment. These findings highlight the value of postoperative echocardiographic assessment and the need for further studies with early and long-term follow-up. This study provides novel regional data from Iran and supports the need for larger prospective studies to validate these findings.
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