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Multidimensional Mechanisms of Hypertension and Advances in Diagnosis and Integrated TCM-Based Treatment: A Review

Aoli Chen1, Ruifeng Chen1, Ying Zhang1

  • 1Department of Cardiology, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200062, People's Republic of China.

International Journal of General Medicine
|April 30, 2026
PubMed

Insights

Traditional Chinese Medicine (TCM) shows potential for managing hypertension by reducing blood pressure and protecting blood vessels. Further rigorous research is needed to confirm its clinical value and standardize treatments.

Area of Science:

  • Cardiovascular Medicine
  • Integrative Medicine
  • Pharmacology

Background:

  • Hypertension is a significant global cardiovascular, cerebrovascular, and renal health burden.
  • Complex etiology involves metabolic, environmental, lifestyle, and genetic factors, leading to population heterogeneity.
  • Understanding these multidimensional mechanisms is crucial for effective management.

Purpose of the Study:

  • To review the multidimensional mechanisms of hypertension.
  • To summarize recent diagnostic advancements.
  • To examine the role and evidence of Traditional Chinese Medicine (TCM) in hypertension management.

Main Methods:

  • Literature review of experimental and clinical studies on hypertension mechanisms and TCM interventions.
  • Analysis of diagnostic techniques like ambulatory and home blood pressure monitoring.
  • Evaluation of TCM approaches including herbal formulas and acupuncture.

Main Results:

  • TCM interventions may reduce blood pressure, offer vascular protection, and improve inflammatory/metabolic status via multi-target effects.
  • Evidence suggests TCM's potential through integrated TCM-Western medicine approaches.
  • Current evidence is limited by small sample sizes and methodological heterogeneity.

Conclusions:

  • Hypertension management needs integration of modern diagnostics, precision medicine, digital health, and TCM.
  • Rigorous evaluation of TCM-based and integrative strategies is essential.
  • Strengthening methodological quality and standardization will clarify TCM's clinical value.
Abstract

Keywords:
hypertensionindividualized treatmentintegrated traditional Chinese and Western medicinepathophysiologytraditional Chinese medicine

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