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Defining Recovery After Gastrectomy: Insights from Longitudinally Collected Patient-Reported Outcomes.

Maho Takayama1, Koichi Tomita1, Paula Marincola Smith1,2

  • 1Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Annals of Surgical Oncology
|April 30, 2026
PubMed
Summary
This summary is machine-generated.

Total gastrectomy is linked to slower recovery after surgery. Patient-reported outcomes reveal variations in recovery based on gastrectomy type, impacting symptom burden and quality of life.

Keywords:
GastrectomyMD Anderson Symptom Inventory SurveyPatient-reported outcomesPostoperative symptom recoveryRobotic approaches

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Area of Science:

  • Oncology
  • Surgical Gastroenterology
  • Patient-Reported Outcomes Research

Background:

  • Longitudinal patient-reported outcomes (PROs) are crucial for understanding symptom burden and functional recovery post-gastrectomy.
  • Benchmarks for recovery and the impact of bodyweight loss on quality of life after different gastrectomy types remain unclear.

Purpose of the Study:

  • To evaluate recovery trajectories using PROs after various gastrectomy procedures.
  • To identify factors associated with recovery and assess the impact of bodyweight changes on quality of life.

Main Methods:

  • Prospective collection of PRO data using the MD Anderson Symptom Inventory from gastrectomy patients.
  • Calculation of symptom and interference composite scores, with recovery defined as mild symptom scores by postoperative month 6.
  • Logistic regression and Spearman correlation analyses to identify recovery predictors and bodyweight associations.

Main Results:

  • Total gastrectomy (TG) patients exhibited greater symptom burden and slower recovery rates compared to other gastrectomy types.
  • Open TG was associated with a failure to recover, unlike robotic TG.
  • Significant bodyweight loss was observed in TG and proximal gastrectomy patients, but it did not correlate with enjoyment-of-life scores.

Conclusions:

  • Total gastrectomy is associated with delayed recovery based on PROs.
  • Postoperative recovery patterns differ significantly among various gastrectomy types, highlighting the need for tailored management strategies.