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HyperHealth: a pilot study on AI-driven COVID-19 detection using hyperspectral fingertip images
Emanuela Marasco1, Shruti Wagle2, Mason Rule3
1Computer Science, Virginia Commonwealth University, Richmond, VA, 23284, USA. marascoe@vcu.edu.
Scientific Reports
|April 30, 2026
Summary
This study introduces a novel AI framework using Hyperspectral Imaging (HSI) to detect COVID-19 from fingertip biometrics. This method offers rapid, non-invasive screening for infectious diseases.
Area of Science:
- Biomedical Engineering
- Artificial Intelligence
- Spectroscopy
Background:
- The need for rapid infectious disease screening persists despite COVID-19 advancements.
- Limited data from COVID-19 positive individuals hinders traditional AI diagnostic methods.
- Hyperspectral Imaging (HSI) shows potential for disease detection.
Purpose of the Study:
- To develop and validate a novel AI-integrated HSI framework for detecting COVID-19 status.
- To demonstrate the feasibility of using fingertip biometric data for infection detection.
- To establish the first publicly available dataset of HSI images from COVID-19 positive individuals.
Main Methods:
- Integration of HSI with Artificial Intelligence (AI) analysis.
- Analysis of high-dimensional spectral signatures from fingertip images.
- Utilized Support Vector Machine (SVM) and Logistic Regression for classification.
Main Results:
- The AI-HSI framework successfully identified distinctive spectral patterns linked to COVID-19.
- Classification algorithms achieved high accuracy in identifying COVID-19 status from HSI images.
- Demonstrated the potential of hyperspectral features for non-invasive health monitoring.
Conclusions:
- The developed AI-HSI framework shows significant potential for non-invasive, real-time infectious disease screening.
- This approach can aid in developing advanced AI-powered diagnostics.
- The creation of a public HSI dataset for COVID-19 advances biometric spectral imaging research.
