Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Assessment of blood pressure in brachial artery(one-step method)

Assessment of blood pressure in brachial artery(one-step method)

This procedural guide systematically measures blood pressure using an oscillometric digital sphygmomanometer, emphasizing accuracy, patient safety, and comfort.
Prepare for the Procedure:

Guidelines For Measuring Vital Signs

Guidelines For Measuring Vital Signs

Following these guidelines can help nurses accurately measure vital signs, assess changes in patient conditions, and provide timely treatment when necessary. Adhering closely to the guidelines ensures the accuracy and reliability of the results.
Before taking a patient's vital signs, a nurse would consider and assess the patient's comfort level and ensure appropriate equipment is available.

Pharmaceutical Poisoning: Potential Scenarios

Pharmaceutical Poisoning: Potential Scenarios

Pharmaceutical poisoning can occur through various channels, impacting an estimated 2 million hospitalized patients in the U.S. annually with serious adverse drug responses. These scenarios encompass both therapeutic uses, such as drug toxicity, where even standard dosages can lead to severe central nervous system depression, and non-therapeutic exposures, including accidental ingestion by children, and environmental and occupational exposures.Unintentional poisonings often involve exploratory...

Pre-Procedural Guidelines for Assessing Blood Pressure

Pre-Procedural Guidelines for Assessing Blood Pressure

Accurate blood pressure assessment is crucial for diagnosing and managing various health conditions. To ensure the reliability of these measurements, healthcare professionals must adhere to standardized pre-procedural guidelines. These guidelines enhance patient safety and improve the overall quality of healthcare. The following steps are essential for obtaining accurate and consistent blood pressure readings, from using the appropriate tools to ensuring effective communication with the...

Guidelines for Nursing Documentation II

Guidelines for Nursing Documentation II

Effective documentation is an integral part of nursing practice. Here are some essential guidelines to follow when documenting patient care:
Timely documentation is crucial to ensure continuity of care for patients. Any delays in recording or reporting medical information can result in medical errors and even adverse patient outcomes. From medication administration to diagnostic test results, every detail must be accurately and promptly documented to provide the best possible care for patients.

Pneumothorax-I

Pneumothorax-I

A pneumothorax is a condition where air builds up in the space between the lung and the chest wall, causing the lung to collapse. This condition arises when air enters the space between the parietal and visceral pleura, disrupting the negative pressure essential for lung inflation. This can lead to a partial or complete collapse of the lung.
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Correction: Shah et al. Visualization of Critical Limits and Critical Values Facilitates Interpretation. <i>Diagnostics</i> 2025, <i>15</i>, 604.

Diagnostics (Basel, Switzerland)·2026

Same author

Oral Hygiene Behaviours, Motivation and Perceived Competence in Adults Living With Mental Illness: A Cross-Sectional Study.

International journal of dental hygiene·2026

Same author

Critical Decision Thresholds for Urgent Physician Notification of Point-of-Care Testing Results.

Diagnostics (Basel, Switzerland)·2026

Same author

Establishing oral care routines among people with mental health challenges: an analysis of a self-regulation intervention using the Capability, Opportunity, Motivation-Behaviour model.

Australian journal of primary health·2026

Same author

Feasibility Study of a Behavioral Oral Health Intervention for People With Mental Health Challenges: A Self-Regulation Approach.

Health science reports·2026

Same author

Development and Evaluation of a Lyophilized Plasma-Based Internal Quality Control for Human Immunodeficiency Virus Rapid Diagnostic Tests.

Diagnostics (Basel, Switzerland)·2026

Search research articles

Related Experiment Video

Updated: May 2, 2026

A Modified Sonographic Algorithm for Image Acquisition in Life-Threatening Emergencies in the Critically Ill Newborn

A Modified Sonographic Algorithm for Image Acquisition in Life-Threatening Emergencies in the Critically Ill Newborn

Published on: April 7, 2023

Drug Critical Limits for Urgent Physician Notification.

Elina Kuang¹, Yasmeen Ibrahim², Kyle Cheng³

¹Department of Neurobiology, Physiology, and Behavior, University of California, Davis, Davis, California, USA.

Clinical Pharmacology and Therapeutics

|April 30, 2026

Summary

US hospitals lack a national standard for drug critical limits, leading to significant inter-institutional variability. This study highlights inconsistencies in critical drug limits, impacting patient safety and necessitating standardized practices.

More Related Videos

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses

Published on: August 30, 2018

Author Spotlight: Microbial Control and Monitoring Strategies for Cleanroom Environments and Cellular Therapies

Author Spotlight: Microbial Control and Monitoring Strategies for Cleanroom Environments and Cellular Therapies

Published on: March 17, 2023

Related Experiment Videos

Last Updated: May 2, 2026

A Modified Sonographic Algorithm for Image Acquisition in Life-Threatening Emergencies in the Critically Ill Newborn

A Modified Sonographic Algorithm for Image Acquisition in Life-Threatening Emergencies in the Critically Ill Newborn

Published on: April 7, 2023

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses

Published on: August 30, 2018

Author Spotlight: Microbial Control and Monitoring Strategies for Cleanroom Environments and Cellular Therapies

Author Spotlight: Microbial Control and Monitoring Strategies for Cleanroom Environments and Cellular Therapies

Published on: March 17, 2023

Area of Science:

Clinical Chemistry
Pharmacology
Health Services Research

Background:

Critical limits for drugs are vital for immediate clinician notification and life-saving interventions.
A lack of a national standard for drug critical limits exists in United States hospitals.
Significant inter-institutional variability in drug critical limits has been observed.

Purpose of the Study:

To assess the current landscape of drug critical limits across US hospitals.
To identify variations in critical limit lists based on hospital characteristics.
To compare hospital practices against established consensus guidelines.

Main Methods:

Collected critical limit data from 417 US hospitals nationwide.
Classified hospitals by US Census division and network-affiliated vs. independent status.
Applied non-parametric statistical analyses to examine critical limits for 111 drugs.

Main Results:

High listing frequencies for digoxin, lithium, acetaminophen, and theophylline were observed.
Significant differences in critical limits were found across US Census divisions and between network-affiliated and independent hospitals.
Discrepancies were noted between listed critical limits and consensus guidelines for several drugs, including acetaminophen, vancomycin, aminoglycosides, immunosuppressants, and psychotropic drugs.

Conclusions:

There is substantial variability in drug critical limits across US hospitals, indicating a need for standardization.
Current critical limit practices may not consistently align with evidence-based guidelines, potentially affecting patient safety.
Sharing critical notification lists is encouraged to foster research and enhance standards of care.