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Updated: May 2, 2026

Mass Spectrometry and Luminogenic-based Approaches to Characterize Phase I Metabolic Competency of In Vitro Cell Cultures
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Endogenous melatonin partial metabolic clearance as a potential endogenous marker of CYP1A2 activity

Akitomo Yokokawa1, Hayato Shimazaki1, Shunji Igarashi1

  • 1Laboratory of Clinical Pharmacy and Experimental Therapeutics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan.

British Journal of Clinical Pharmacology
|May 1, 2026
PubMed
Abstract

Keywords:
6‐hydroxymelatoninCYP1A2LC–MS/MSendogenous phenotypingmelatonin

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