Brain-gut communication and potential applications of microecological treatments in stroke

Stroke is a cerebrovascular disease with high incidence rates, serious disability and increased mortality rates, thereby posing a serious threat to human health. The mechanisms of brain-gut communication have gradually emerged in recent times. This article focuses on the gut-brain axis and discusses the bidirectional regulatory pathways between gut microecology and stroke via the neurotransmitter, colony metabolite, endocrine, and immunoregulatory pathways. Additionally, it summarizes the latest applications of gut microecological agents in stroke, which may provide new research ideas and clinical treatment strategies for the microecological diagnosis and therapy of stroke.