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Related Concept Videos

Esophageal Perforation-I: Introduction01:22

Esophageal Perforation-I: Introduction

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Esophageal perforation is a severe medical condition characterized by a breach in the integrity of the esophageal wall. This breach can occur due to various factors such as trauma, medical procedures, or underlying diseases. When the esophageal wall is compromised, it allows food, fluids, and digestive juices into the chest cavity or adjacent structures, leading to potential complications and health risks.
The location of esophageal perforation can vary, occurring anywhere along the esophagus....
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Esophageal Perforation-II: Clinical Manifestations and Management01:28

Esophageal Perforation-II: Clinical Manifestations and Management

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Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:
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Esophageal Varices-I: Introduction01:24

Esophageal Varices-I: Introduction

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Esophageal varices are dilated, tortuous veins which are found mainly in the submucosa of the lower esophagus but which may also appear higher up or extend into the stomach. They develop due to increased pressure in the portal venous system, often as a result of liver cirrhosis. This condition scars and damages the liver, impeding normal blood flow through the portal vein. To compensate, blood seeks alternative pathways, forming fragile new vessels (varices) in the esophagus and stomach. These...
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Related Experiment Video

Updated: May 2, 2026

Application of Laparoscopic Partial Splenectomy with Total Blood Flow Occlusion in Benign Splenic Lesions
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Spontaneous Splenic Rupture in a Patient With Recent Use of Performance-Enhancing Compounds: A Case Report and

Kumail Jaffry1,2, Jainam Shah1,2, Niyaz Naqash1,2

  • 1Department of General Surgery and Acute Surgery Unit, Monash Health, Melbourne, AUS.

Cureus
|May 1, 2026
PubMed
Summary

Atraumatic splenic rupture (ASR) occurred in a man using performance-enhancing compounds. Prompt diagnosis and management with embolization and splenectomy were crucial for survival.

Area of Science:

  • Medicine
  • Surgery
  • Toxicology

Background:

  • Atraumatic splenic rupture (ASR) is a rare surgical emergency, often linked to underlying splenic abnormalities.
Keywords:
atraumatic splenic rupturesarmsselective androgen receptor modulatorssplenectomyspontaneous splenic rupture

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  • Performance-enhancing compounds, including growth hormone secretagogues and selective androgen receptor modulators (SARMs), are increasingly used in bodybuilding.