Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

2.4K
Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
2.4K
Phases of Wound Repair01:28

Phases of Wound Repair

8.0K
Following injury, the integrity of the injured tissues must be reestablished. For example, in skin tissue, wound repair involves coordination among resident skin cells, blood mononuclear cells, extracellular matrix, growth factors, and cytokines to complete the healing cascade.
Formation of Blood Clot
In case of deep injuries, trauma to blood vessels results in blood loss. In the meantime, phospholipids released from the ruptured endothelial cellular membrane are converted into arachidonic...
8.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Author Correction: Development of Gold coated calcium peroxide nanoparticles for photothermal ferroptosis against skin cancer and C. albicans.

Communications chemistry·2026
Same author

Development of Gold coated calcium peroxide nanoparticles for photothermal ferroptosis against skin cancer and C. albicans.

Communications chemistry·2026
Same author

Esterase-induced release of a theranostic prodrug in lysosomes for improved therapeutic efficacy and lower systemic toxicity.

Chemical science·2025
Same author

Advances in Nanomedicine for Cancer Theranostics.

Biomedical materials (Bristol, England)·2025
Same author

Investigation for the pro-angiogenic properties of eggshell-derived nanoparticles.

Biomedical materials (Bristol, England)·2025
Same author

Folic acid-encapsulated silver nitroprusside nanoparticles for targeted therapy in ovarian cancer.

Biomedical materials (Bristol, England)·2025
Same journal

Molecularly designed star-shaped PLA-based polymers with enhanced piezoelectricity for ultrasound-driven wound healing.

Journal of materials chemistry. B·2026
Same journal

Self-powered thermoelectric gel dressings for chronic wound monitoring and therapy.

Journal of materials chemistry. B·2026
Same journal

An ultrasound-responsive lipoic acid-based bioadhesive for oral mucosal wound repair.

Journal of materials chemistry. B·2026
Same journal

Functional group effects on mephedrone adsorption in UiO-66-type metal-organic frameworks.

Journal of materials chemistry. B·2026
Same journal

Tanshinone IIA nano-liposomes ameliorate cerebral ischemia-reperfusion injury associated with activation of the PGK1/Nrf2 signalling axis.

Journal of materials chemistry. B·2026
Same journal

A low-cost titanium suboxide pH sensor with competitive operational lifetime assessed with electrochemical impedance spectroscopy.

Journal of materials chemistry. B·2026
See all related articles

Related Experiment Video

Updated: May 2, 2026

Formulation of Zinc-Based Nanomaterials using the Eucommia ulmoides Bark Extract and their Wound Healing Potential
06:54

Formulation of Zinc-Based Nanomaterials using the Eucommia ulmoides Bark Extract and their Wound Healing Potential

Published on: December 27, 2024

833

Eggshell-derived nanoparticles accelerate wound healing.

Proma Nagchowdhury1,2, Swapnali Londhe1,2, Sanchita Tripathy1,2

  • 1Department of Applied Biology, CSIR-Indian Institute of Chemical Technology, Uppal Road, Tarnaka, Hyderabad - 500007, Telangana State, India. crpatra.iict@csir.res.in.

Journal of Materials Chemistry. B
|May 1, 2026
PubMed
Summary
This summary is machine-generated.

Eggshell-derived nanoparticles (ES-NP) promote wound healing by enhancing angiogenesis. Studies show ES-NP accelerate wound closure in mice, suggesting therapeutic potential for chronic wounds.

More Related Videos

Chessboard-like Burn Wound Healing Model of Mice Based on Digital Heating Device
04:04

Chessboard-like Burn Wound Healing Model of Mice Based on Digital Heating Device

Published on: December 27, 2024

1.9K
Optimizing Extracellular Vesicle Delivery Using a Core-Sheath 3D-Bioprinted Scaffold for Chronic Wound Management
09:17

Optimizing Extracellular Vesicle Delivery Using a Core-Sheath 3D-Bioprinted Scaffold for Chronic Wound Management

Published on: February 28, 2025

927

Related Experiment Videos

Last Updated: May 2, 2026

Formulation of Zinc-Based Nanomaterials using the Eucommia ulmoides Bark Extract and their Wound Healing Potential
06:54

Formulation of Zinc-Based Nanomaterials using the Eucommia ulmoides Bark Extract and their Wound Healing Potential

Published on: December 27, 2024

833
Chessboard-like Burn Wound Healing Model of Mice Based on Digital Heating Device
04:04

Chessboard-like Burn Wound Healing Model of Mice Based on Digital Heating Device

Published on: December 27, 2024

1.9K
Optimizing Extracellular Vesicle Delivery Using a Core-Sheath 3D-Bioprinted Scaffold for Chronic Wound Management
09:17

Optimizing Extracellular Vesicle Delivery Using a Core-Sheath 3D-Bioprinted Scaffold for Chronic Wound Management

Published on: February 28, 2025

927

Area of Science:

  • Biomaterials Science
  • Regenerative Medicine
  • Nanotechnology

Background:

  • Chronic wounds represent a significant global health challenge.
  • Normal wound healing involves four stages: hemostasis, inflammation, proliferation, and remodeling.
  • Angiogenesis, crucial for the proliferative phase, is vital for effective wound repair.

Purpose of the Study:

  • To investigate the therapeutic efficacy of eggshell-derived nanoparticles (ES-NP) for wound healing.
  • To demonstrate the pro-angiogenic properties of ES-NP through in vitro and in vivo studies.
  • To evaluate ES-NP as a potential treatment for acute and chronic wounds.

Main Methods:

  • In vitro assays using human keratinocytes (HaCaT cells): MTT assay, thymidine incorporation, cell cycle/apoptosis analysis, ROS generation, immunocytochemistry.
  • In vivo studies using a pre-clinical mouse model (C57BL/6).
  • Histopathological analysis: H&E staining, immunohistochemistry (Ki-67, CD31/PECAM), Masson's trichrome staining.

Main Results:

  • ES-NP demonstrated significant pro-angiogenic properties in vitro.
  • Treatment with ES-NP significantly accelerated wound closure in the mouse model compared to controls.
  • Histological analysis confirmed enhanced re-epithelialization, vascularization (CD31), and collagen deposition in ES-NP treated tissues.

Conclusions:

  • Eggshell-derived nanoparticles (ES-NP) possess therapeutic potential for wound healing.
  • ES-NP promote key cellular events including keratinocyte proliferation and angiogenesis.
  • ES-NP are a promising candidate for treating wounds and conditions where angiogenesis is critical.