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Updated: May 2, 2026

Testing Sensory and Multisensory Function in Children with Autism Spectrum Disorder
Published on: April 22, 2015
On the Spectrum: High-Functioning Autism and Its Contemporary Relevance
J Michael Bostwick1, Alastair J S McKean1
1Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN.
The Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-5) reconceptualized autism, increasing prevalence. Adults with autism spectrum disorder often struggle with social and occupational functioning, necessitating comprehensive care.
Area of Science:
- Neurodevelopmental Disorders
- Psychiatry
- Public Health
Background:
- The DSM-5 revision in 2013 expanded the definition of autism spectrum disorder (ASD).
- This reconceptualization led to a near doubling of ASD prevalence in the United States.
- Asperger disorder, now part of ASD, is frequently diagnosed in adulthood due to subtle presentation.
Purpose of the Study:
- To highlight the diagnostic shift and increased prevalence of autism spectrum disorder post-DSM-5.
- To describe the characteristics and challenges faced by adults with undiagnosed autism spectrum disorder.
- To inform nonpsychiatric providers about recognizing and managing ASD comorbidities in adults.
Main Methods:
- Review of diagnostic criteria changes in DSM-5.
- Analysis of prevalence data shifts following DSM-5 publication.
- Discussion of clinical manifestations and management strategies for adult ASD.
Main Results:
- Autism spectrum disorder prevalence increased to over 2% of the US population.
- Adults with high-functioning autism often present with social and occupational difficulties.
- Comorbid psychiatric and physical conditions are common in adults with ASD.
Conclusions:
- Adult diagnosis of autism spectrum disorder is increasingly recognized, often presenting with social and employment challenges.
- Addressing comorbidities and providing targeted support services are crucial for mitigating suffering and enhancing function in adults with ASD.
- Interdisciplinary care, including referrals for employment support, occupational therapy, and psychotherapy, can improve outcomes for adults with autism spectrum disorder.
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