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Related Concept Videos

Adrenal Gland Disorders01:27

Adrenal Gland Disorders

3.7K
Adrenal gland disorders manifest when the production of adrenal hormones deviates from the norm, resulting in either excessive or insufficient concentrations.
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
3.7K
Hormonal Regulation01:33

Hormonal Regulation

30.4K
The renin-aldosterone system is an endocrine system which guides the renal absorption of water and electrolytes, thus managing blood pressure and osmoregulation. Activation of the system begins in the kidneys with a small cluster of cells adjacent to the afferent and efferent blood vessels of the renal corpuscle. As the nephrons are filtering blood, juxtaglomerular cells monitor blood pressure. If they detect a decrease in pressure, they release the hormone renin into the bloodstream.
30.4K
Hormones of the Adrenal Glands01:31

Hormones of the Adrenal Glands

5.9K
Adrenal hormones play a pivotal role in maintaining the body's electrolyte balance and orchestrating responses to stress, showcasing the intricate functions of the adrenal cortex and medulla.
The adrenal cortex, a powerhouse of hormone synthesis, generates over two dozen corticosteroid hormones. The zona glomerulosa produces mineralocorticoids, exemplified by aldosterone, influencing the electrolyte composition of body fluids. The synthesis of glucocorticoids such as cortisol and...
5.9K
Cushing Syndrome II: Pathophysiology01:19

Cushing Syndrome II: Pathophysiology

24
Cortisol production is normally governed by the hypothalamic–pituitary–adrenal (HPA) axis, which maintains hormonal balance through tightly regulated feedback mechanisms. Disruption of this regulatory system is central to the development of Cushing syndrome, whether the excess cortisol originates from external medications or internal pathology. Persistent cortisol elevation alters metabolism, immune function, and endocrine signaling, producing the characteristic clinical features...
24
Cushing Syndrome I: Introduction01:26

Cushing Syndrome I: Introduction

36
Cushing syndrome refers to the collection of clinical manifestations that arise when tissues are exposed to excessive amounts of cortisol or cortisol-like medications over an extended period. Cortisol, a glucocorticoid produced by the adrenal cortex, regulates metabolism, immune responses, and the body’s adaptation to stress. When its concentration remains chronically elevated, these physiological pathways become dysregulated, resulting in the characteristic features of the...
36
Anatomy of the Adrenal Glands01:17

Anatomy of the Adrenal Glands

5.7K
The adrenal or supra-renal glands, situated above the kidneys and aligned with the twelfth rib, are paired pyramid-shaped structures crucial for the body's stress response. During stress, these glands secrete hormones vital for adaptive physiological reactions.
These glands possess a distinctive yellow tinge due to the stored cholesterol and fatty acids required for hormone synthesis. They are encased in a fibrous capsule and cushioned by fat.
The adrenal gland comprises two distinct...
5.7K

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Updated: May 3, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
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Adrenal Disorders in Pregnancy.

Justin Mathew1, Alyssa Yeung2

  • 1Division of Endocrinology, Department of Medicine, Montefiore Medical Center, Bronx, NY, USA.

Endocrinology and Metabolism Clinics of North America
|May 1, 2026
PubMed
Summary
This summary is machine-generated.

Adrenal disorders during pregnancy are uncommon but serious. Early diagnosis and tailored treatments, including surgery or medication, are crucial for managing conditions like Cushing

Keywords:
AdrenalAdrenal cortical carcinomaCortisolCushing syndromeHyperaldosteronismPheochromocytomaPregnancy

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Area of Science:

  • Endocrinology
  • Obstetrics
  • Reproductive Medicine

Background:

  • Adrenal disorders in pregnancy present diagnostic challenges due to overlapping physiological changes.
  • These conditions are rare but carry significant clinical implications for both mother and fetus.
  • Timely diagnosis, ideally prior to conception, is paramount for optimal management.

Purpose of the Study:

  • To review the diagnostic challenges and management strategies for adrenal disorders during pregnancy.
  • To highlight the importance of early identification and intervention for specific adrenal conditions.

Main Methods:

  • Literature review of adrenal disorders in pregnant patients.
  • Analysis of diagnostic overlaps with normal pregnancy physiology.
  • Summary of current treatment modalities for various adrenal conditions.

Main Results:

  • Cushing's syndrome and adrenal cortical carcinoma typically require surgical intervention.
  • Primary aldosteronism is often managed medically.
  • Pheochromocytoma management includes medical treatment, with surgery as an option.
  • Adrenal insufficiency is manageable with medical therapy and dose adjustments.

Conclusions:

  • Effective management of adrenal disorders in pregnancy relies on accurate diagnosis and individualized treatment plans.
  • Surgical and medical interventions are tailored to specific conditions such as Cushing's syndrome, primary aldosteronism, pheochromocytoma, and adrenal insufficiency.
  • Close monitoring and dose adjustments are essential for managing adrenal insufficiency during pregnancy.