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Published on: October 25, 2018
Introduction to Nanotechnology in Dermatology
Sakshi Verma1, Prottay Dutta2, Pran Kishore Deb3
1Department of Pharmacy, Usha Martin University, Ranchi, India; Department of Pharmaceutical Sciences and Technology, Birla Institute of Technology, Mesra, Ranchi, India.
None:
Nanotechnology has been one of the major fields that revolutionized biomedical science, enabling new diagnostics, therapy, and cosmetic dermatological applications. Nanomaterials are capable of overcoming the difficulties of the complex skin structure due to their ability to change size, having a large surface area, and permeating through biological barriers. The chapter gives a detailed review of nanotechnology applications in dermatology, starting with the basics and structure of skin barriers. Focus is made on the role of nanocarriers in skincare and cosmetics, with regard to the delivery of active ingredients, including how such products are used. The application of nanocarriers in dermatology and personal care, and the scientific mechanism behind the improved penetration of active ingredients through the stratum corneum and epidermis, is discussed. Many people are interested in how nanotechnology can aid in wound healing and whether it is applicable to human beings.The chapter analyses safety, toxicity and regulatory concerns, emphasizing on risk evaluation and ethical paradigm. The final sections discuss clinical translation, scalability, long-term safety and potential applications in personalised and precision dermatology.The purpose of this chapter is to provide academicians, clinicians, and industry the knowledge of the radical changes resulting from nanotechnology to the science (knowledge), treatment practices, and commercial enterprise of dermatology. The discussion underscores the potential of nanomedicine to improve patient outcomes as well as shape the future of preventive and cosmetic components of skin health.
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