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Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

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Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...

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Related Experiment Video

Updated: May 4, 2026

Visualizing Macrophage Extracellular Traps Using Confocal Microscopy

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Published on: October 19, 2017

Viral Infection-Associated Plastic Bronchitis Demonstrating Eosinophil Extracellular Trap Formation

Yusuke Iwata¹, Hidehito Ota¹, Takahito Koba¹

¹Department of Pediatrics, The University of Tokyo School of Medicine, Tokyo, Japan.

Pediatric Pulmonology

|May 2, 2026

Summary

No abstract available in PubMed .

Keywords:

Airway Obstruction Charcot‐Leyden crystals Programmed Cell Death

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