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Optimizing Early Psychosis Care through Family Psychoeducation: A Systematic Review and Meta-Analysis
Thiago A Benazzi1, Vicente R Arturi2, Luis H T da Silva3
1Graduate Program in Psychiatry and Behavioral Sciences, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil. Laboratory of Molecular Psychiatry, Centro de Pesquisa Experimental, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil.
Family psychoeducation significantly improves clinical outcomes for individuals with first-episode psychosis (FEP), reducing hospitalizations and symptom severity. This accessible intervention supports integration into early care programs.
Area of Science:
- Psychiatry and Mental Health
- Evidence-Based Practice
- Health Services Research
Background:
- Family psychoeducation is a crucial psychosocial intervention in early psychosis care.
- Its specific impact on relatives of individuals with first-episode psychosis (FEP) requires further clarification.
Purpose of the Study:
- To systematically review and meta-analyze the clinical and caregiver outcomes of family psychoeducation for FEP.
- To evaluate the effectiveness of structured family psychoeducation programs compared to usual care.
Main Methods:
- Systematic review and meta-analysis adhering to PRISMA guidelines, registered in PROSPERO.
- Searched major databases (PubMed, Embase, Scopus, Cochrane Library) for randomized and nonrandomized trials up to April 2024.
- Included 15 studies with 2,271 participants.
Main Results:
- Family psychoeducation reduced psychiatric hospitalizations (RR 0.64) and inpatient stays (SMD -0.29).
- Significant symptom improvements observed: general psychopathology (SMD -0.45), positive symptoms (SMD -0.36), and negative symptoms (SMD -0.32), with lasting effects on negative symptoms at two years.
- No significant effects found on patient functioning or caregiver burden.
Conclusions:
- Family psychoeducation is a cost-effective and feasible intervention for FEP.
- It demonstrably improves patient clinical outcomes and reduces healthcare service utilization.
- Supports the integration of family psychoeducation into early intervention services for psychosis.
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