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Indian Fungal Infection National Declaration (I-FIND): India's Response to Fungal Diseases
Vinaykumar Hallur1, Jayanthi Savio2, Shukla Das3
1Department of Microbiology, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.
Background:
Serious fungal diseases are significant yet long neglected public health problem in India, affecting an estimated 4.1% of the population and with the mortality from invasive fungal diseases approaching 50%, surpassing several nationally prioritised conditions. The emergence and spread of drug resistant pathogens such as Candidozyma auris formerly Candida auris, azole resistant Aspergillus fumigatus, and Trichophyton indotineae together with COVID-19 associated mucormycosis epidemic, exposes critical gaps in preparedness, prevention, and care. Despite the presence of a WHO collaborating centre and an Indian Council of Medical Research (ICMR) Advanced Mycology Diagnostic and Research Centre network, major deficiencies persist in surveillance, diagnostics, antifungal access, stewardship, workforce, capacity and coordinated research.
Objectives:
The Indian Fungal Infection National Declaration (I- FIND) seeks to catalyse a structured, time bound national response that elevates fungal diseases to a recognised public health priority and measurably reduces morbidity, mortality, and fungal resistance. Its objectives are to identify and target key at risk populations (including those with immunosuppression, critical illnesses, chronic lung disease and poorly controlled diabetes), to acknowledge major community mycoses such as chronic dermatophytosis, vulvovaginal candidiasis, and fungal keratitis, and to define clear domains for action across governance, surveillance, diagnostics, clinical management, research, workforce development, public awareness, One Health, and accountability.
Content:
I- FIND identifies 9 core domains, including governance, surveillance, diagnostics, clinical management, research, workforce development, public awareness, One Health measures, and accountability. Proposals cover creating a National Task Force, issuing a five-year fungal disease control strategy, integrating mycology network, setting diagnostic standards, incorporating stewardship and prioritizing translational research funding. The declaration supported by major Indian and international professional societies, guides formal adoption and implementation across India.
Insights
Serious fungal infections are a major public health issue in India, causing significant mortality. The Indian Fungal Infection National Declaration (I-FIND) aims to establish a national strategy to combat these diseases and reduce their impact.
Area of Science:
- Public Health
- Infectious Diseases
- Mycology
Background:
- Serious fungal diseases are a neglected public health problem in India, affecting an estimated 4.1% of the population.
- High mortality rates from invasive fungal diseases, drug-resistant pathogens (e.g., Candida auris, azole-resistant Aspergillus fumigatus), and COVID-19-associated mucormycosis highlight critical gaps in preparedness and care.
- Deficiencies exist in surveillance, diagnostics, antifungal access, stewardship, workforce, capacity, and coordinated research despite existing networks.
Purpose of the Study:
- To catalyze a structured, time-bound national response to elevate fungal diseases as a public health priority in India.
- To measurably reduce morbidity, mortality, and fungal resistance through targeted interventions.
- To identify at-risk populations and acknowledge major community mycoses, defining clear action domains.
Main Methods:
- The Indian Fungal Infection National Declaration (I-FIND) outlines 9 core domains for action: governance, surveillance, diagnostics, clinical management, research, workforce development, public awareness, One Health, and accountability.
- Proposals include establishing a National Task Force, a five-year fungal disease control strategy, integrating mycology networks, and setting diagnostic standards.
- The declaration emphasizes antifungal stewardship and prioritizing translational research funding.
Main Results:
- I-FIND identifies key at-risk populations and major community mycoses requiring attention.
- It defines clear domains for action across multiple sectors to address fungal infections comprehensively.
- The declaration provides a framework for national implementation and adoption.
Conclusions:
- I-FIND seeks to elevate fungal diseases to a recognized public health priority in India.
- It proposes a multi-faceted strategy to improve surveillance, diagnostics, treatment, and research.
- The declaration is supported by major professional societies, guiding its formal adoption and implementation across India.
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