Related Experiment Video
Updated: May 4, 2026
A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
Continuous Hemodynamic Monitoring During Transcatheter Tricuspid Valve Repair: Insights From Pulse Contour-based
Sandra Uhle1, Mathias H Konstandin2, Benedikt Alt-Epping1
1Department of Anesthesiology, Heidelberg University Hospital, Heidelberg, Germany.
Objectives:
This exploratory pilot study was designed to evaluate the effectiveness of pulse contour analysis (PCA) for real-time hemodynamic monitoring in patients undergoing transcatheter edge-to-edge tricuspid valve repair (T-TEER). Additionally, it examined whether continuous PCA monitoring can identify indicators of procedural success and improve perioperative management.
Design:
Prospective, hypothesis-generating pilot, single-center study.
Setting:
Single tertiary care university hospital.
Participants:
A total of 12 patients undergoing T-TEER.
Interventions:
Real-time PCA was used throughout the intervention period, from preoperative assessment up to 4 hours postprocedure, to monitor hemodynamic parameters (cardiac output [CO], cardiac index [CI], stroke volume, stroke volume variation, and blood pressure).
Measurements And Main Results:
At 4 hours after T-TEER, CO-PCA had increased by 30% (p = 0.0124), accompanied by a 0.68-L/min/m² rise in CI (p = 0.008). T-TEER also resulted in a persistent reduction in stroke volume variation-PCA, with a sustained 3% decrease after the intervention (p = 0.009). Implantation of the first device triggered a notable peri-interventional increase in systolic arterial pressure of 17 mmHg (p = 0.026). In addition, the right atrial v-wave decreased by 8 mmHg (p = 0.034). No meaningful changes in central venous oxygen saturation or central venous pressure were detected during or following the procedure (p = 0.73 and p = 0.27, respectively).
Conclusions:
This study demonstrated that PCA using FloTrack monitoring can provide valuable continuous hemodynamic information and characterize acute hemodynamic responses to T-TEER. PCA detected meaningful hemodynamic improvements during T-TEER, characterized by increased CO, enhanced CI, and more stable preload conditions.
