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Updated: May 4, 2026
10:19
Screening and Identification of RNA Silencing Suppressors from Secreted Effectors of Plant Pathogens
Published on: February 3, 2020
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A Virus-Inducible E3-RLCK-MADS Module Coordinates Suppression of Plant Immunity and Fertility in Rice
Yuansheng Wu1, Fengling Wu1, Shiting Huang1
1State Key Laboratory of Agriculture and Forestry Biosecurity, Center For Genetic Improvement, Vector-borne Virus Research Center, College of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou, China.
Summary
Rice grassy stunt virus (RGSV) manipulates plant fertility by triggering a protein degradation cascade. This virus-induced pathway links antiviral defense and reproductive regulation, impacting pollen viability and susceptibility to infection.
Area of Science:
- Plant molecular biology
- Virology
- Plant immunity
Background:
- Viruses exploit host developmental pathways for infection.
- The interplay between plant reproductive regulation and antiviral immunity is not fully understood.
Purpose of the Study:
- To elucidate the molecular mechanisms linking antiviral immunity and fertility regulation in rice.
- To identify key components of a virus-triggered regulatory cascade.
Main Methods:
- Genetic analysis of rice mutants (mads1, mads15, rlck22).
- Biochemical assays to investigate protein interactions and degradation.
- Transcriptional profiling of plant responses to viral infection.
Main Results:
- Rice grassy stunt virus (RGSV) effector P3 activates E3 ubiquitin ligase P3IP1.
- P3IP1 targets RLCK22 for degradation, destabilizing MADS1/15 transcription factors.
- Loss of RLCK22 impairs pollen viability and increases viral susceptibility.
Conclusions:
- A virus-inducible E3-RLCK-MADS axis regulates both plant development and defense.
- Pathogens can manipulate plant fitness via targeted protein degradation pathways.
- This study provides novel insights into host-pathogen interactions affecting plant reproduction.
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