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Updated: May 5, 2026

Plaque Assay for Murine Norovirus
10:53

Plaque Assay for Murine Norovirus

Published on: August 22, 2012

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Pathogenic characteristics, epidemiology, and diagnostic methods of murine norovirus

Jikai Li1, Maiqi Gao2, Xiaolong Ma3

  • 1School of Public Health, North China University of Science and Technology, Tangshan 063210, China.

Research in Veterinary Science
|May 3, 2026
PubMed

Insights

Murine Norovirus (MNV) significantly impacts laboratory mice and research outcomes. This review details MNV

Area of Science:

  • Veterinary Virology
  • Laboratory Animal Science
  • Infectious Disease Epidemiology

Background:

  • Murine Norovirus (MNV) identified in 2003 is a prevalent pathogen in laboratory mice.
  • MNV poses significant risks to the quality of research animals and experimental data.
  • Understanding MNV is crucial for maintaining reliable research models.

Purpose of the Study:

  • To review the pathogenic characteristics of Murine Norovirus.
  • To summarize the epidemiological distribution of MNV in mouse colonies.
  • To outline diagnostic methods for MNV detection and control.

Main Methods:

  • Literature review of scientific publications on Murine Norovirus.
  • Synthesis of data on MNV pathogenesis, epidemiology, and diagnostics.
  • Analysis of existing strategies for MNV prevention and control.

Main Results:

  • MNV exhibits diverse pathogenic effects impacting mouse health and physiology.
  • Widespread epidemiological distribution of MNV necessitates vigilant monitoring.
  • Various diagnostic techniques are available for MNV identification.

Conclusions:

  • Comprehensive understanding of MNV is essential for effective prevention and control strategies.
  • Implementing robust diagnostic and management protocols can mitigate MNV's impact.
  • This review provides a framework for safeguarding the integrity of research involving laboratory mice.
Keywords:
Diagnostic methodsEpidemiologyInfectionLaboratory miceMurine norovirus

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