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Updated: May 5, 2026

Real-time Electrophysiology: Using Closed-loop Protocols to Probe Neuronal Dynamics and Beyond
Published on: June 24, 2015
Physics-informed Koopman learning approach for fixed-time synchronization of stochastic neural dynamics.
1Vellore Institute of Technology, Department of Mathematics, Vellore, 632014, India.
This study introduces a physics-informed Koopman framework for fixed-time synchronization of Hindmarsh-Rose neurons under noise. It achieves guaranteed convergence and handles communication limits using a dynamic event-triggering mechanism.
Area of Science:
- Computational Neuroscience
- Nonlinear Dynamics
- Control Theory
Background:
- Hindmarsh-Rose neurons exhibit complex nonlinear dynamics.
- Synchronization of neural systems is crucial for understanding brain function.
- Existing methods struggle with noise and fixed-time convergence.
Purpose of the Study:
- To develop a physics-informed Koopman operator framework for fixed-time synchronization of Hindmarsh-Rose neurons.
- To design a non-singular fixed-time controller robust to noise.
- To incorporate a dynamic event-triggering mechanism for communication efficiency.
Main Methods:
- Koopman operator theory to linearize nonlinear neuronal dynamics in a higher-dimensional space.
- Physics-informed lifting dictionary derived from HR neuron algebraic nonlinearities.
- Non-singular fixed-time control design and dynamic event-triggering mechanism (DETM).
Main Results:
- The proposed framework achieves guaranteed fixed-time synchronization for Hindmarsh-Rose neurons.
- The controller ensures convergence within a predefined time, independent of initial conditions.
- The DETM effectively manages communication bandwidth limitations.
Conclusions:
- The physics-informed Koopman framework provides an effective approach for fixed-time neural synchronization.
- The study demonstrates robustness against mixed Gaussian and Poisson jump noise.
- The developed control strategy is suitable for resource-constrained communication environments.
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