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Related Experiment Videos

Acute monocytic arthritis.

A E Brawer, E S Cathcart

    Arthritis and Rheumatism
    |March 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    This study examined five patients with fever, rash, and acute polyarthritis. Synovial fluid analysis revealed inflammatory effusions, and biopsies showed vasculitis, suggesting a link to viral arthritis or hypersensitivity angiitis.

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    Area of Science:

    • Rheumatology
    • Pathology
    • Internal Medicine

    Background:

    • Acute polyarthritis, fever, and skin rash present a diagnostic challenge.
    • Synovial fluid analysis and tissue biopsies are crucial for diagnosing inflammatory joint conditions.

    Purpose of the Study:

    • To investigate the synovial fluid characteristics and histopathology in patients presenting with the triad of fever, skin rash, and acute polyarthritis.

    Main Methods:

    • Analysis of synovial fluid from five patients.
    • Skin biopsies from two patients.
    • Synovial membrane biopsy from one patient.

    Main Results:

    • All patients exhibited inflammatory synovial effusions with a predominance of monocytes.

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  • Histopathological examination revealed non-necrotizing vasculitis in skin and synovial tissues.

    • Conclusions:

    • The findings suggest non-necrotizing vasculitis in patients with fever, rash, and acute polyarthritis.
    • The syndrome shares similarities with viral arthritides and warrants consideration as acute hypersensitivity angiitis.