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An Electrospun Fibrous Eye Mask with Antibacterial and Antioxidant Functions
Xinhang Duan1, Leting Wang1, Chuxuan Cheng2
1School of Materials and Chemistry, University of Shanghai for Science and Technology, Shanghai 200093, China.
Biomolecules
|May 4, 2026
Summary
This study introduces a novel coaxial electrospun eye mask with dual antibacterial and antioxidant properties. The innovative design effectively combats microbial infections and oxidative stress for enhanced eye care.
Area of Science:
- Biomaterials Science
- Ophthalmology
- Nanotechnology
Background:
- Standard eye masks lack therapeutic features for ocular infections and inflammation.
- Blended electrospinning results in inhomogeneous distribution of therapeutic agents.
Purpose of the Study:
- To develop a coaxial electrospun nanofibrous eye mask with dual antibacterial and antioxidant functions.
- To provide an innovative ocular treatment tool for improved eye care.
Main Methods:
- Coaxial electrospinning technique to create a core-shell structured bilayer membrane.
- Preparation of polycaprolactone-polylysine/polyvinyl alcohol-resveratrol (PCL-PLs/PVA-RSV) membrane.
- Loading resveratrol in the PVA core and polylysine in the PCL shell.
Main Results:
- Successful preparation of a uniform fiber morphology with favorable hydrophilicity.
- Demonstrated significant inhibition of *Staphylococcus aureus* and *Escherichia coli* growth.
- Exhibited excellent free radical scavenging ability and sustained release of therapeutic agents.
Conclusions:
- The core-shell design facilitates sustained release and long-term antioxidant effects.
- The multifunctional eye mask offers a synergistic approach against microbial infection and oxidative stress.
- This platform shows significant potential for advanced eye care applications.
