Evaluation of the Reliability of Radiographic and MRI Angles in Superior Femoral Epiphysiolysis: A Comparative Study
Wassim Ben Abdennebi1, Andreas Tsoupras1, Eugénie Barras2
1Paediatric Orthopaedics and Traumatology Unit, Geneva University Hospitals, University of Geneva, 1205 Geneva, Switzerland.
Abstract:
Background/Objectives: Slipped Capital Femoral Epiphysis (SCFE) is a common, serious hip disorder in children and adolescents. Two-dimensional (2D) radiography is the gold standard for diagnosis but may not fully capture the deformity's complexity, and it is vulnerable to positioning errors. Advances in three-dimensional (3D) imaging, such as computed tomography and magnetic resonance imaging (MRI), enable more accurate assessments. This study aimed to (1) assess the inter-rater reliability of 2D radiographic and 3D MRI measurements, and (2) evaluate the correlations and agreements between these outcomes. Methods: Patients were randomly selected from a cohort of patients aged under 16 years old and diagnosed with SCFE between January 2000 and December 2024. Southwick angles and posterior epiphyseal slip angles on 2D radiographs were independently measured by two orthopaedic surgeons. Posterior epiphyseal slip angles on 3D MRI were independently measured by two orthopaedic surgeons and two paediatric radiologists. Relationships between the three outcomes were evaluated using the Pearson correlation coefficient (r). Inter-rater reliability and agreements between the three outcomes were evaluated using the intraclass correlation coefficient (ICC) and the standard error measurement (SEM). Results: A total of 35 patients (35 hips) were recruited, with a mean age of 11.8 (1.2) years old and 19/35 (54%) females. Radiographic outcomes were moderately correlated (r < 0.75, p < 0.01) with MRI posterior epiphyseal slip angles. MRI posterior epiphyseal slip angles were systematically greater (16° on average) than both radiographic outcomes, regardless of whether contralateral correction was applied. The inter-rater reliability of radiographic outcomes was excellent (ICC > 0.85, SEM > 5.0°) and almost perfect (ICC > 0.95, SEM = 2.5°) for the MRI posterior epiphyseal slip angles measured by the paediatric radiologists. Conclusions: Findings suggest that while both diagnostic methods are reliable, radiographic measurements systematically underestimate epiphyseal slip severity by approximately 16° compared to MRI. This discrepancy could impact the accuracy of disease staging, leading to potential misclassifications. This highlights the need for a more standardised approach to evaluating SCFE, especially regarding the type of imaging used for angle measurement.


