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Published on: June 21, 2024
Determinants of Chemotherapy Convenience and Satisfaction: The Role of Symptom and Psychological Burden in Cancer
Evangelos C Fradelos1, Konstantinos Skampardonis1, Pavlos Sarafis2
1Laboratory of Clinical Nursing, Department of Nursing, University of Thessaly, 41500 Larissa, Greece.
Background:
Chemotherapy-related symptom burden and psychological distress may significantly influence patients' perceptions of treatment convenience and satisfaction, yet evidence in the Greek oncology population remains limited.
Methods:
A cross-sectional study was conducted among 150 cancer patients receiving chemotherapy in a tertiary hospital. Data were collected using CCSQ, ESAS-r, PHQ-2, GAD-2, and WHO-5. Pearson correlations and multiple linear regression analyses were performed.
Results:
Higher levels of depressive symptoms and anxiety were significantly associated with lower chemotherapy convenience and satisfaction (e.g., PHQ-2: r = -0.659 to -0.584, p < 0.001; GAD-2: r = -0.623 to -0.469, p < 0.001). Depressed mood emerged as a significant negative predictor of convenience (β = -0.39, p = 0.015) and concerns (β = -0.39, p = 0.005), while anxiety independently predicted satisfaction (β = 0.45, p = 0.007).
Conclusions:
Chemotherapy experience is strongly associated with psychological and symptom burden. These findings highlight the importance of integrating psychosocial assessment into routine oncology care.
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