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Artificial Intelligence vs. Human Experts in Temporomandibular Joint MRI Interpretation: A Systematic Review
Marijus Leketas1,2, Inesa Stonkutė1, Miglė Miškinytė2
1Faculty of Odontology, Medical Academy, Lithuanian University of Health Sciences, J. Lukšos-Daumanto 2, LT-50106 Kaunas, Lithuania.
Healthcare (Basel, Switzerland)
|May 4, 2026
Summary
Artificial intelligence (AI) shows diagnostic performance comparable to experienced clinicians for temporomandibular joint (TMJ) MRI analysis. AI models are promising decision-support tools but should complement, not replace, expert radiological assessment.
Area of Science:
- Radiology
- Artificial Intelligence
- Medical Imaging
Background:
- Magnetic resonance imaging (MRI) is the gold standard for evaluating temporomandibular joint (TMJ) disorders.
- Artificial intelligence (AI) and deep learning offer potential advancements in medical image analysis.
- Increasing imaging demands necessitate efficient and accurate diagnostic tools.
Purpose of the Study:
- To systematically review and compare the diagnostic performance of AI models against human experts in TMJ MRI analysis.
- To assess the potential of AI as an adjunct tool for radiologists interpreting TMJ MRIs.
- To evaluate AI's effectiveness in identifying specific TMJ pathologies.
Main Methods:
- Systematic review adhering to PRISMA 2020 guidelines, registered in PROSPERO.
- Comprehensive search of major scientific databases (PubMed, ScienceDirect, etc.) for studies from 2020-2026.
- Inclusion of studies comparing AI/ML/DL models against human expert interpretation for TMJ MRI, extracting sensitivity, specificity, accuracy, and AUC.
Main Results:
- Five retrospective studies (118-1474 patients) evaluated AI for TMJ disorders like disc displacement and osteoarthritis.
- AI models demonstrated strong discriminative performance (AUC 0.79-0.98), achieving accuracy comparable to experienced radiologists.
- AI showed higher specificity and similar overall accuracy, while human experts often had higher sensitivity; AI performance neared expert levels for osteoarthritis.
Conclusions:
- AI achieves diagnostic performance comparable to experienced clinicians in TMJ MRI interpretation.
- AI shows significant promise as a decision-support tool for TMJ disorder assessment.
- Further rigorous validation is required before AI can be fully integrated as a complementary tool to expert radiological assessment.

