Central European Sample Analysis of Traumatic Vertebral Fractures: A One-Year Retrospective Cohort Study

The purpose of this study was to examine the sex-specific distribution of traumatic spinal fractures and potential predictive clinical factors for a more well-founded treatment evaluation.

This study is a retrospective cohort study. Data from electronic medical records were analyzed and compiled in a database. Demographic information, trauma-specific characteristics, and radiological measurements, as well as laboratory values and surgical treatments, were collected. Only surgical cases were included in this study. Statistical analyses were performed using the IBM SPSS Statistics program. Chi-square tests, effect sizes, and 95 confidence intervals were used for comparison of categorical variables, and means and standard deviations were calculated, as well as Levene's test for equality and t-tests for analyzing continuous variables. The statistical significance was set at a two-tailed p < 0.05.

A total of 164 patients were included, with a mean age of 58.03 years. Statistically significant differences between sexes were found in age (p = 0.04), GCS (p = 0.03), hemoglobin (p = 0.03), hematocrit (p = 0.007), and the one-year post-surgical intervertebral angle (p = 0.004). AIS score showed statistically significant differences in the cervical and lumbar sections (p < 0.015; p = 0.022) and the overall spine (p = 0.049). No statistically significant difference in the HU values in the vertebra above the fracture was found between men and women. Women showed significantly larger one-year postoperative intervertebral angles than men.

Vertebrae with lower HU values tend to collapse despite stable surgical treatment; therefore, additional bone quality assessment should be contemplated. These findings highlight sex-specific considerations for future clinical decision-making.