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Related Concept Videos

Colloidal precipitates01:09

Colloidal precipitates

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The high insolubility of some precipitates can result in an unfavorable relative supersaturation. This can lead to colloidal particles with a large surface-to-mass ratio, where adsorption is promoted. For instance, in the precipitation of silver chloride, silver ions are adsorbed on the surface of the colloidal particles, forming a primary layer. This layer attracts ions of opposite charge (such as nitrate ions), forming a diffuse secondary layer of adsorbed ions. This electric double layer...
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Optimized Isolation of White Tea Infusion Micro-Nanoparticles and Stability Mechanism: A

Yuan Sun1, Chuyu Ye1, Fei Xu1

  • 1College of Food Science and Engineering, Ocean University of China, Qingdao 266404, China.

Foods (Basel, Switzerland)
|May 4, 2026
PubMed
Summary

Researchers optimized white tea infusion micro-nanoparticles (WTMPs) isolation using ultrafiltration-centrifugation. The study reveals WTMPs possess enhanced stability and a remodeled composition, with enriched gallic acid (GA) and reduced caffeine (CAF).

Keywords:
TOPSISmolecular dynamicsmulti-spectroscopic analysisstabilitywhite tea micro-nanoparticles

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Area of Science:

  • Food Science
  • Colloid Science
  • Biophysics

Background:

  • White tea infusion micro-nanoparticles (WTMPs) are crucial for colloidal stability.
  • Optimal isolation strategies and stability mechanisms for WTMPs are not well understood.

Purpose of the Study:

  • To optimize the isolation of WTMPs using ultrafiltration-centrifugation.
  • To elucidate the composition-structure-stability relationship of isolated WTMPs.
  • To understand the roles of gallic acid (GA) and caffeine (CAF) in WTMP stability.

Main Methods:

  • Multi-indicator TOPSIS strategy for optimizing ultrafiltration-centrifugation parameters (100 kDa membrane, 3000× g, 20 min).
  • Characterization of isolated WTMPs using spectroscopy.
  • Molecular dynamics simulations to investigate molecular interactions.

Main Results:

  • Optimized isolation yielded WTMPs with remodeled composition, regular morphology, ordered structure, and improved stability.
  • Gallic acid (GA) was selectively enriched, while caffeine (CAF) content decreased significantly.
  • GA promotes cooperative interfacial stabilization, whereas CAF acts as a local ligand in the protein-polysaccharide network.

Conclusions:

  • Established an optimal method for isolating stable WTMPs with enhanced properties.
  • Demonstrated a clear link between WTMP composition, structure, and environmental stability.
  • Provided mechanistic insights into the stabilization roles of GA and CAF in white tea systems.