Porcine Skin-Derived Silver Nanoparticles: A Novel Green Synthesis Approach and Molecular Characterization of Their
Kyoung Ran Kim1, Bummo Koo1, Min Woo Lee2
1Department of Health and Safety Convergence Science, Graduate School, Korea University, 145 Anam-ro, Seoul 02841, Republic of Korea.
Abstract:
Silver nanoparticles (AgNPs) are widely recognized for their potent antibacterial properties and diverse biomedical applications. While conventional synthesis methods typically rely on chemical-reducing agents that may pose risks to human health and the environment, this study proposes an eco-friendly green synthesis approach utilizing porcine skin extracts. The extracts were prepared through thermal treatment and filtration to serve as a biological reducing agent. Successful synthesis was validated using dynamic light scattering, Fourier transform infrared (FTIR) spectroscopy, UV-Vis spectroscopy, and scanning electron microscopy (SEM). Furthermore, the antimicrobial efficacy of the synthesized AgNPs was evaluated against multidrug-resistant microorganisms, demonstrating significant growth inhibition across various antibiotic-resistant strains. These findings suggest that porcine skin-a readily available bioresource-is a promising precursor for the sustainable production of AgNPs with broad-spectrum antimicrobial potential.
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