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Updated: May 5, 2026

Multidisciplinary Approach to Obesity Management: A Case Report
Published on: May 30, 2025
Management of Childhood Obesity
Hoda Gad1, Hajar Dauleh2, Idris Mohammed2
1Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON M5T 3H7, Canada.
Insights
Childhood obesity involves excess fat accumulation, impacting health and quality of life. Management requires a multidisciplinary approach, including lifestyle changes and targeted therapies based on genetic causes for effective treatment.
Area of Science:
- Pediatrics
- Endocrinology
- Genetics
Background:
- Obesity is defined as excess adipose tissue accumulation, linked to metabolic and cardiac issues.
- Numerous factors contribute to obesity, including genetics, environment, and behavior.
- Obesity is associated with severe complications like diabetes, hypertension, and liver disease.
Purpose of the Study:
- To provide a comprehensive review of current childhood obesity management strategies.
- To highlight the importance of a patient-centered, multidisciplinary approach.
- To emphasize precision-guided therapy based on genetic etiology.
Main Methods:
- Literature review of current research on obesity management.
- Analysis of contributing factors and associated complications.
- Classification of childhood obesity causes (polygenic, monogenic, syndromic, endocrine).
Main Results:
- Obesity management requires integrating lifestyle changes with pharmacotherapy and surgery.
- Identifying genetic causes enables tailored and more effective treatments.
- A multidisciplinary approach is crucial for patient-centered care.
Conclusions:
- Effective childhood obesity management necessitates a personalized, multidisciplinary strategy.
- Understanding genetic underpinnings allows for precision medicine in treating obesity.
- This review synthesizes state-of-the-art approaches for pediatric obesity care.
Abstract:
Obesity is characterized by an excess accumulation of adipose tissue, independent of its distribution or function, and is associated with organ dysfunction and a broad range of metabolic and cardiac complications. Nutritional, environmental, behavioral, genetic, psychological, and metabolic factors contribute to obesity. It is associated with many secondary complications, including diabetes mellitus, hypertension, dyslipidemia, metabolic dysfunction-associated steatotic liver disease, reduced quality of life, and psychological illnesses. For practical purposes, childhood obesity can be classified into polygenic, monogenic, syndromic, and endocrine causes. Management should be patient-centered and multidisciplinary, integrating lifestyle/behavioral changes with adjunctive pharmacotherapy and bariatric surgery where appropriate. In monogenic or syndromic obesity, knowing the underlying genetic etiology allows precision-guided and more effective therapy. This review aims to provide a state-of-the-art review on the management of obesity in children.
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