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Stress Fracture in Athletes: A Practical Approach
Federica Presutti1, Stefano Paoletti1, Francesca Conte2
1Departmental Faculty of Medicine and Surgery, UniCamillus Saint Camillus International University of Health Sciences, 00131 Rome, Italy.
Journal of Clinical Medicine
|May 4, 2026
Summary
Stress fractures (SFs) are common overuse injuries in athletes. This review synthesizes evidence on SFs, emphasizing modifiable risk factors like training errors and low energy availability for better athlete management.
Area of Science:
- Sports Medicine
- Orthopedics
- Exercise Physiology
Background:
- Stress fractures (SFs) are a significant overuse injury in athletes, marking a severe stage of bone stress injuries (BSIs).
- These injuries stem from repetitive mechanical stress surpassing bone's adaptive capacity, leading to performance decline and extended athletic absence.
- Effective management is crucial to prevent recurrence, highlighting the need for evidence-based strategies.
Purpose of the Study:
- To provide a clinically focused review of current evidence on stress fractures in athletes.
- To emphasize modifiable risk factors, including training load errors, neuromuscular fatigue, and Relative Energy Deficiency in Sport (RED-S).
- To propose a practical framework for diagnosis, management, and prevention to optimize athlete care.
Main Methods:
- A narrative review synthesizing existing research on SF epidemiology, pathophysiology, risk factors, diagnosis, management, and prevention.
- Emphasis on modifiable contributors within the RED-S framework.
- Discussion of a stepwise diagnostic approach including clinical assessment, lab tests, and MRI for severity grading.
Main Results:
- Diagnostic evaluation integrates clinical findings, lab work, and MRI, with MRI serving as the gold standard for early detection and grading.
- A risk-based management framework combines MRI severity and anatomical site to guide treatment and return-to-sport decisions.
- Low-risk SFs often resolve with conservative care, while high-risk fractures may necessitate closer monitoring or surgical intervention.
Conclusions:
- A practical clinical framework is proposed to aid decision-making for suspected or confirmed SFs in athletes.
- The framework aims to enhance early diagnosis, optimize treatment strategies, and minimize the risk of SF recurrence.
- Integrating evidence on modifiable factors and advanced diagnostics can improve outcomes in sports medicine practice.

