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Updated: May 5, 2026

Detecting the Lyme Disease Spirochete, Borrelia Burgdorferi, in Ticks Using Nested PCR
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Imported Pediatric Lyme Disease in Singapore-A Case Series

Ade Xin Ning Tan1, Ilyas Hussin1, Chia Yin Chong2,3,4,5

  • 1Department of Pediatrics, KK Women's and Children's Hospital, Singapore 229899, Singapore.

Pathogens (Basel, Switzerland)
|May 4, 2026
PubMed

Insights

Imported Lyme disease, a tick-borne illness, can affect children traveling from endemic areas. This case series highlights varied presentations and diagnostic challenges for clinicians in non-endemic regions like Singapore.

Area of Science:

  • Infectious Diseases
  • Pediatrics
  • Epidemiology

Background:

  • Lyme disease is a prevalent tick-borne illness in North America and Europe.
  • While uncommon in Singapore, imported cases pose a risk, particularly for travelers.
  • Understanding varied clinical presentations is crucial for timely diagnosis.
Keywords:
Lyme diseasemeningitispediatricprior antibiotic therapy

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