Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Instability of nitroglycerin tablets.

G A Mayer

    Canadian Medical Association Journal
    |April 6, 1974
    PubMed
    Summary
    This summary is machine-generated.

    Proper storage is crucial for maintaining nitroglycerin tablet potency. Storing nitroglycerin in a refrigerator in tightly capped amber bottles and limiting bottle opening preserves the medication for 3-5 months.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Stamps of Canadian medical interest.

    Canadian Medical Association journal·2010
    Same author

    The saccharin ban.

    Canadian Medical Association journal·2010
    Same author

    Fibrinolysin Therapy of Thrombophlebitis and Pulmonary Embolism.

    Canadian Medical Association journal·2010
    Same author

    Hematocrit and coronary artery disease.

    Canadian Medical Association journal·2010
    Same author

    Chlorpropamide or chlorpromazine?

    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne·1991
    Same author

    Blood viscosity and oral anticoagulant therapy.

    American journal of clinical pathology·1976

    Area of Science:

    • Pharmacology
    • Pharmaceutical Science

    Background:

    • Nitroglycerin is a volatile medication prone to evaporation.
    • Improper storage significantly reduces nitroglycerin's therapeutic efficacy.

    Purpose of the Study:

    • To determine optimal storage conditions for nitroglycerin tablets.
    • To establish guidelines for maintaining nitroglycerin potency.

    Main Methods:

    • Comparative analysis of nitroglycerin tablet stability under various storage conditions.
    • Assessment of potency degradation based on storage duration and environmental factors.

    Main Results:

    • Refrigerated, tightly capped amber bottles preserve nitroglycerin potency for 3-5 months with weekly opening.
    • Tablets stored in pill boxes deteriorate within a week.

    Related Experiment Videos

  • Materials like cotton, plastic, or paper, and frequent bottle opening accelerate nitroglycerin degradation.

    • Conclusions:

    • Strict adherence to recommended storage protocols is essential for nitroglycerin efficacy.
    • Healthcare providers and manufacturers must educate patients on proper nitroglycerin storage to prevent premature deterioration.